Enzymatic synthesis and function of folylpolyglutamates.
about
Analysis of folylpoly-gamma-glutamate synthetase gene expression in human B-precursor ALL and T-lineage ALL cellsUpstream organization of and multiple transcripts from the human folylpoly-gamma-glutamate synthetase geneMurine cytomegalovirus stimulates cellular thymidylate synthase gene expression in quiescent cells and requires the enzyme for replicationFolate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamicsConcentration-dependent processivity of multiple glutamate ligations catalyzed by folylpoly-gamma-glutamate synthetase.Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation.Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.Transcription of the human folylpoly-gamma-glutamate synthetase gene.The specific features of methionine biosynthesis and metabolism in plants.Streptococcus pneumoniae folate biosynthesis responds to environmental CO2 levelsIncreased production of folate by metabolic engineering of Lactococcus lactisEffects of cultivation conditions on folate production by lactic acid bacteria.Synthesis of (6R)- and (6S)-5,10-dideazatetrahydrofolate oligo-gamma-glutamates: kinetics of multiple glutamate ligations catalyzed by folylpoly-gamma-glutamate synthetaseRegulation of folylpoly-gamma-glutamate synthesis in bacteria: in vivo and in vitro synthesis of pteroylpoly-gamma-glutamates by Lactobacillus casei and Streptococcus faecalisFolate metabolism as a source of molecular targets for antimalarials.Mechanisms of antifolate resistance and methotrexate efficacy in leukemia cells.A domino effect in antifolate drug action in Escherichia coli.Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.Role of hepatic tetrahydrofolate in the species difference in methanol toxicity.Pharmacokinetics and metabolism of methotrexate: an example for the use of clinical pharmacology in pediatric oncology.Rescue after intermediate and high-dose methotrexate: background, rationale, and current practice.Gene polymorphisms in the folate metabolism and their association with MTX-related adverse events in the treatment of ALL.Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.Controlled modulation of folate polyglutamyl tail length by metabolic engineering of Lactococcus lactis.Isotachophoretic analysis of the dihydrofolate reductase reaction in the presence of methotrexate and ascorbic acid.Collateral methotrexate resistance in cisplatin-selected murine leukemia cells.Chronic cobalamin inactivation impairs folate polyglutamate synthesis in the ratRapid decline in folylpolyglutamate synthetase activity and gene expression during maturation of HL-60 cells. Nature of the effect, impact on folate compound polyglutamate pools, and evidence for programmed down-regulation during maturation.γ-Glutamyl hydrolase modulation significantly influences global and gene-specific DNA methylation and gene expression in human colon and breast cancer cells.Neural tube and craniofacial defects with special emphasis on folate pathway genes.Effects of tetrahydrofolate polyglutamates on the kinetic parameters of serine hydroxymethyltransferase and glycine decarboxylase from pea leaf mitochondria.Interaction between glycine decarboxylase, serine hydroxymethyltransferase and tetrahydrofolate polyglutamates in pea leaf mitochondria.Characterization of the role of para-aminobenzoic acid biosynthesis in folate production by Lactococcus lactis.Biochemistry and Physiology of Vitamins in Euglena.Core pathways operating during methylotrophy of Bacillus methanolicus MGA3 and induction of a bacillithiol-dependent detoxification pathway upon formaldehyde stress.Mitochondria are a major site for folate and thymidylate synthesis in plants.Vitamins
P2860
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P2860
Enzymatic synthesis and function of folylpolyglutamates.
description
1981 nî lūn-bûn
@nan
1981 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1981 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
name
Enzymatic synthesis and function of folylpolyglutamates.
@ast
Enzymatic synthesis and function of folylpolyglutamates.
@en
Enzymatic synthesis and function of folylpolyglutamates.
@nl
type
label
Enzymatic synthesis and function of folylpolyglutamates.
@ast
Enzymatic synthesis and function of folylpolyglutamates.
@en
Enzymatic synthesis and function of folylpolyglutamates.
@nl
prefLabel
Enzymatic synthesis and function of folylpolyglutamates.
@ast
Enzymatic synthesis and function of folylpolyglutamates.
@en
Enzymatic synthesis and function of folylpolyglutamates.
@nl
P2860
P356
P1476
Enzymatic synthesis and function of folylpolyglutamates.
@en
P2093
Bertino JR
McGuire JJ
P2860
P2888
P356
10.1007/BF00235686
P478
38 Spec No
P577
1981-08-01T00:00:00Z
P6179
1053251813