The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions
about
GPR91: expanding the frontiers of Krebs cycle intermediatesSUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes.Sites of superoxide and hydrogen peroxide production by muscle mitochondria assessed ex vivo under conditions mimicking rest and exerciseMaintenance of homeostasis in the aging hypothalamus: the central and peripheral roles of succinate.Tissue-specific transcriptome assemblies of the marine medaka Oryzias melastigma and comparative analysis with the freshwater medaka Oryzias latipesSerial plasma metabolites following hypoxic-ischemic encephalopathy in a nonhuman primate model.Identification of lead compounds for (99m)Tc and (18)F GPR91 radiotracersThe Succinate Receptor GPR91 Is Involved in Pressure Overload-Induced Ventricular Hypertrophy.Exome sequencing in one family with gastric- and rectal cancer.An integrated mechanism of pediatric pseudotumor cerebri syndrome: evidence of bioenergetic and hormonal regulation of cerebrospinal fluid dynamics.Regulation of Vascular and Renal Function by Metabolite ReceptorsSirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells.GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.Low affinity GPCRs for metabolic intermediates: challenges for pharmacologists.Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy.Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice.Mitochondrial metabolites: undercover signalling molecules.G protein-coupled receptor 91 signaling in diabetic retinopathy and hypoxic retinal diseases.GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice.Good news-bad news: the Yin and Yang of immune privilege in the eye.Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission.Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock.Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model.Ancylostoma ceylanicum infective third-stage larvae are activated by co-culture with HT-29-MTX intestinal epithelial cells.LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate-G-protein couple receptor 91 (GPR91) pathway in mice.Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota.Biochemistry of proinflammatory macrophage activation.Metabolic profiling of the three neural derived embryonal pediatric tumors retinoblastoma, neuroblastoma and medulloblastoma, identifies distinct metabolic profiles.Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling.Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial MetabolismSuccinate as a Regulator of Hepatic Stellate Cells in Liver Fibrosis
P2860
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P2860
The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The succinate receptor as a no ...... olic stress-related conditions
@ast
The succinate receptor as a no ...... olic stress-related conditions
@en
The succinate receptor as a no ...... olic stress-related conditions
@nl
type
label
The succinate receptor as a no ...... olic stress-related conditions
@ast
The succinate receptor as a no ...... olic stress-related conditions
@en
The succinate receptor as a no ...... olic stress-related conditions
@nl
prefLabel
The succinate receptor as a no ...... olic stress-related conditions
@ast
The succinate receptor as a no ...... olic stress-related conditions
@en
The succinate receptor as a no ...... olic stress-related conditions
@nl
P2860
P356
P1476
The succinate receptor as a no ...... olic stress-related conditions
@en
P2093
Joris Hubertus Robben
Peter Meinardus T Deen
P2860
P356
10.3389/FENDO.2012.00022
P577
2012-02-16T00:00:00Z