Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors. - Wikidata - awgldk - TriplyDB

Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors.

Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors.

http://www.wikidata.org/entity/Q34282667

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The other genome: a systematic review of studies of mitochondrial DNA haplogroups and outcomes of HIV infection and antiretroviral therapy The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity Mitochondrial DNA depletion and fatal infantile hepatic failure due to mutations in the mitochondrial polymerase γ (POLG) gene: a combined morphological/enzyme histochemical and immunocytochemical/biochemical and molecular genetic study In vivo assessment of mitochondrial toxicity of metacavir in Rhesus monkeys after three months of intravenous administration.Tenofovir renal toxicity targets mitochondria of renal proximal tubules.Heart failure in patients with human immunodeficiency virus infection: epidemiology, pathophysiology, treatment, and future research.Tenofovir-associated bone density loss.Accumulation of mitochondrial DNA mutations in human immunodeficiency virus-infected patients treated with nucleoside-analogue reverse-transcriptase inhibitors Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.Aging and HIV/AIDS: pathogenetic role of therapeutic side effects Human immunodeficiency virus/acquired immunodeficiency syndrome and infertility: emerging problems in the era of highly active antiretrovirals.Zidovudine exposure in HIV-1 infected Tanzanian women increases mitochondrial DNA levels in placenta and umbilical cords European mitochondrial DNA haplogroups and metabolic changes during antiretroviral therapy in AIDS Clinical Trials Group Study A5142 Mitochondrial toxicity studied with the PBMC of children from the Chinese national pediatric highly active antiretroviral therapy cohort.Portable lactate analyzer for measuring lactate in cerebrospinal fluid (CSF) and plasma - method-comparison evaluations Mechanisms of zidovudine-induced mitochondrial toxicity and myopathy.Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.Evidence of Subclinical mtDNA Alterations in HIV-Infected Pregnant Women Receiving Combination Antiretroviral Therapy Compared to HIV-Negative Pregnant Women.Protective effect of calycosin-7-O-β-D-glucopyranoside against oxidative stress of BRL-3A cells induced by thioacetamide.Does mitochondrial dysfunction during antiretroviral therapy in human immunodeficiency virus infection suggest antioxidant supplementation as a beneficial option?A novel mechanism of selectivity against AZT by the human mitochondrial DNA polymerase.A brief overview of mechanisms of mitochondrial toxicity from NRTIs.Lamivudine-Induced Liver Injury.Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration.The Molecular and Pharmacological Mechanisms of HIV-Related Neuropathic Pain.Mitochondrial DNA impairment in nucleoside reverse transcriptase inhibitor-associated cardiomyopathy Pharmacogenetics of nucleoside reverse-transcriptase inhibitor-associated peripheral neuropathy Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy Coconut Oil Extract Mitigates Testicular Injury Following Adjuvant Treatment with Antiretroviral Drugs.High frequency of mitochondrial DNA mutations in HIV-infected treatment-experienced individuals.Nucleoside reverse transcriptase inhibitor toxicity and mitochondrial DNA.Central role of mitochondria in drug-induced liver injury.Fidelity of the human mitochondrial DNA polymerase.Cardiomyocytes are Protected from Antiretroviral Nucleoside Analog-Induced Mitochondrial Toxicity by Overexpression of PGC-1α.Mitochondrial purine and pyrimidine metabolism and beyond.Pro-oxidant properties of AZT and other thymidine analogues in macrophages: implication of the azido moiety in oxidative stress.Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism Mitochondrial and Oxidative Stress Response in HepG2 Cells Following Acute and Prolonged Exposure to Antiretroviral Drugs.Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)--2',3'-dideoxycytidine (ddC): relevance to HIV-dementia AZT-induced oxidative cardiovascular toxicity: attenuation by Mg-supplementation.

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Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors.

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The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance

Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme

Oxidants, antioxidants, and the degenerative diseases of aging

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma

Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

Cardiomyopathy associated with antiretroviral therapy in patients with HIV infection: a report of six cases

Ultrastructural characteristics and DNA immunocytochemistry in human immunodeficiency virus and zidovudine-associated myopathies

Mitochondrial myopathy caused by long-term zidovudine therapy

Inhibitory effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks

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