Kinetic proofreading in T-cell receptor signal transduction.
about
Conformational proofreading: the impact of conformational changes on the specificity of molecular recognitionAntagonist HIV-1 Gag peptides induce structural changes in HLA B8An induced rebinding model of antigen discriminationFunctional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptorA feeling for the numbers in biologyHarmonic oscillator model of the insulin and IGF1 receptors' allosteric binding and activationHigh fidelity of RecA-catalyzed recombination: a watchdog of genetic diversityQuantitative challenges in understanding ligand discrimination by alphabeta T cellsPartially phosphorylated Pho4 activates transcription of a subset of phosphate-responsive genesModeling T cell antigen discrimination based on feedback control of digital ERK responsesFrom kinetics and cellular cooperations to cancer immunotherapiesAction and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseTCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of DifferentiationIdentifying Individual T Cell Receptors of Optimal Avidity for Tumor AntigensStructural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC DiscriminationExperimental and theoretical bases for mechanisms of antigen discrimination by T cellsαβ TCR-mediated recognition: relevance to tumor-antigen discovery and cancer immunotherapyIndoctrinating T cells to attack pathogens through homeschoolingMechanical regulation of T-cell functionsT cell antigen recognition at the cell membraneEpitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complexSelective Ligand Recognition by a Diversity-Generating Retroelement Variable ProteinSpecificity and completion time distributions of biochemical processesMicrophysiometric analysis of human alpha1a-adrenoceptor expressed in Chinese hamster ovary cellsMaladaptation and the paradox of robustness in evolutionUnderstanding diseases by mouse click: the promise and potential of computational approaches in Systems BiologyMechanisms and implications of air pollution particle associations with chemokinesFunctional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO MutationTotal Internal Reflection with Fluorescence Correlation Spectroscopy: Nonfluorescent CompetitorsSequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling.Persistence of cooperatively stabilized signaling clusters drives T-cell activationT-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APCFast rebinding increases dwell time of Src homology 2 (SH2)-containing proteins near the plasma membrane.Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC.DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity.Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS.A role for rebinding in rapid and reliable T cell responses to antigenClass II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function.The SCHOOL of nature: I. Transmembrane signaling.Variant antigenic peptide promotes cytotoxic T lymphocyte adhesion to target cells without cytotoxicity
P2860
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P2860
Kinetic proofreading in T-cell receptor signal transduction.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Kinetic proofreading in T-cell receptor signal transduction.
@ast
Kinetic proofreading in T-cell receptor signal transduction.
@en
Kinetic proofreading in T-cell receptor signal transduction.
@nl
type
label
Kinetic proofreading in T-cell receptor signal transduction.
@ast
Kinetic proofreading in T-cell receptor signal transduction.
@en
Kinetic proofreading in T-cell receptor signal transduction.
@nl
prefLabel
Kinetic proofreading in T-cell receptor signal transduction.
@ast
Kinetic proofreading in T-cell receptor signal transduction.
@en
Kinetic proofreading in T-cell receptor signal transduction.
@nl
P2860
P356
P1476
Kinetic proofreading in T-cell receptor signal transduction.
@en
P2093
McKeithan TW
P2860
P304
P356
10.1073/PNAS.92.11.5042
P407
P577
1995-05-01T00:00:00Z