Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development. - Wikidata - awgldk - TriplyDB

Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.

Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.

http://www.wikidata.org/entity/Q34286592

about

WNT-5A: signaling and functions in health and disease Role and regulation of β-catenin signaling during physiological liver growth Wnt and planar cell polarity signaling in cystic renal disease Analysis of neural crest-derived clones reveals novel aspects of facial development.Non-canonical WNT signalling in the lung Activation of intracellular calcium by multiple Wnt ligands and translocation of β-catenin into the nucleus: a convergent model of Wnt/Ca2+ and Wnt/β-catenin pathways Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres Molecular Signaling of Progesterone, Growth Hormone, Wnt, and HER in Mammary Glands of Dogs, Rodents, and Humans: New Treatment Target Identification.Induction of WNT inhibitory factor 1 expression by Müllerian inhibiting substance/antiMullerian hormone in the Müllerian duct mesenchyme is linked to Müllerian duct regression.Bone marrow mesenchymal stem cell-derived Wnt5a inhibits leukemia cell progression in vitro via activation of the non-canonical Wnt signaling pathway.Expression of Wnt-5a and β-catenin in primary hepatocellular carcinoma.Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a Intersection of AHR and Wnt signaling in development, health, and disease.Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities Non-canonical Wnt5a/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extension.Dynamic interaction between astrocytes and infiltrating PBMCs in context of neuroAIDS Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.Wnt5a through noncanonical Wnt/JNK or Wnt/PKC signaling contributes to the differentiation of mesenchymal stem cells into type II alveolar epithelial cells in vitro.Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall Discovery of piRNAs Pathway Associated with Early-Stage Spermatogenesis in Chicken β-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis.Expression Pattern of Axin2 During Chicken Development Over-expression of ROR2 and Wnt5a cooperatively correlates with unfavorable prognosis in patients with non-small cell lung cancer.Molecular mechanism of Hoxd13-mediated congenital malformations in rat embryos.Upregulation of the expression of Wnt5a promotes the proliferation of pancreatic cancer cells in vitro and in a nude mouse model Expression of Wnt5a and its receptor Fzd2 is changed in the spinal cord of adult amyotrophic lateral sclerosis transgenic mice.A study of the relationship between the Wnt/β-catenin signaling pathway and the gastrointestinal development of rat embryonic and perinatal periods.Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling.The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis.Wnt signaling during cochlear development.Wnt-signalling in the embryonic mammary gland.Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis.Wnt5a regulates the cell proliferation and adipogenesis via MAPK-independent pathway in early stage of obesity.GSK-3β Inhibition Suppresses Instability-induced Osteolysis by a Dual Action on Osteoblast and Osteoclast Differentiation.A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib.Vertebrate Axial Patterning: From Egg to Asymmetry.Wnt5a inhibited human trophoblast cell line HTR8/SVneo invasion: implications for early placentation and preeclampsia.The WNT-less wonder: WNT-independent β-catenin signaling.

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Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.

http://www.wikidata.org/entity/Q34286592

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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Wnt5a can both activate and re ...... g mouse embryonic development.

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Wnt5a can both activate and re ...... g mouse embryonic development.

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Wnt5a can both activate and re ...... g mouse embryonic development.

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type

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Wnt5a can both activate and re ...... g mouse embryonic development.

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Wnt5a can both activate and re ...... g mouse embryonic development.

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Wnt5a can both activate and re ...... g mouse embryonic development.

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Wnt5a can both activate and re ...... g mouse embryonic development.

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Wnt5a can both activate and re ...... g mouse embryonic development.

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J.YDBIO.2012.06.020

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Developmental Biology

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Christophe Fuerer

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Makiko Mizutani

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Renée van Amerongen

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Roel Nusse

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P2860

LDL-receptor-related proteins in Wnt signal transduction

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

A member of the Frizzled protein family mediating axis induction by Wnt-5A

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

Lrp5 functions in bone to regulate bone mass

Wnt/beta-catenin signaling: components, mechanisms, and diseases

Wnt signal transduction pathways

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

Wnt5 signaling in vertebrate pancreas development.

Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development

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101-114

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