Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.
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1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cellsActivation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferationCloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmanninA role for the POU-III transcription factor Brn-4 in the regulation of striatal neuron precursor differentiationInhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cellsRapamycin and mTOR kinase inhibitorsInduction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells.Phosphoinositides: tiny lipids with giant impact on cell regulationThe Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cellsAntifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionInvolvement of both G protein alphas and beta gamma subunits in beta-adrenergic stimulation of vascular L-type Ca(2+) channelsWortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionRequirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transportA role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophagesActivation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton.Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammationNon-opsonic phagocytosis of Legionella pneumophila by macrophages is mediated by phosphatidylinositol 3-kinasePlatelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinasePiracy of decay-accelerating factor (CD55) signal transduction by the diffusely adhering strain Escherichia coli C1845 promotes cytoskeletal F-actin rearrangements in cultured human intestinal INT407 cells.Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptorPI3K: from the bench to the clinic and back.A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipidsPhosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylationRegulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by Fc epsilon R1 cross-linking.Biotin uptake into human peripheral blood mononuclear cells increases early in the cell cycle, increasing carboxylase activities.Inhibition by wortmannin of M-current in bullfrog sympathetic neuronesA role of protein kinase C mu in signalling from the human adenosine A1 receptor to the nucleusPharmacological modulation of autophagy to protect cardiomyocytes according to the time windows of ischaemia/reperfusion.Myosin light chain kinase-independent inhibition by ML-9 of murine TRPC6 channels expressed in HEK293 cells.Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis.Role of PI4K and PI3K-AKT in ERK1/2 activation by GnRH in the pituitary gonadotropes.PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport.Mast cell tumor necrosis factor alpha production is regulated by MEK kinasesRecruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinaseDifferent sensitivity to wortmannin of two vacuolar sorting signals indicates the presence of distinct sorting machineries in tobacco cells.Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation.
P2860
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P2860
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.
description
1993 nî lūn-bûn
@nan
1993 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@ast
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@en
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@nl
type
label
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@ast
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@en
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@nl
prefLabel
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@ast
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@en
Inhibition of histamine secret ...... tol 3-kinase in RBL-2H3 cells.
@nl
P2093
P1476
Inhibition of histamine secret ...... itol 3-kinase in RBL-2H3 cells
@en
P2093
Nakanishi S
Nonomura Y
P304
25846-25856
P407
P577
1993-12-01T00:00:00Z