AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis.
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Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interactionPR-Set7 establishes a repressive trans-tail histone code that regulates differentiationRUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory elementTescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expressionMegakaryocyte biology and related disordersERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specificationCyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidizationThe contribution of mouse models to the understanding of constitutional thrombocytopeniaTranscription factor-mediated reprogramming toward hematopoietic stem cellsIsoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features.Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiationThe RUNX genes: gain or loss of function in cancerTwist-2 controls myeloid lineage development and functionSox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cellsLuteinizing hormone-induced RUNX1 regulates the expression of genes in granulosa cells of rat periovulatory folliclesRunt-related transcription factor 1 regulates luteinized hormone-induced prostaglandin-endoperoxide synthase 2 expression in rat periovulatory granulosa cellsRunx1 function in hematopoiesis is required in cells that express TekMOZ is essential for maintenance of hematopoietic stem cellsMonocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cellsHematopoiesis: an evolving paradigm for stem cell biologyMegakaryocytic programming by a transcriptional regulatory loop: A circle connecting RUNX1, GATA-1, and P-TEFb.CBFbeta is critical for AML1-ETO and TEL-AML1 activity.Transcriptional control of megakaryocyte development.Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expressionPEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesisA Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation.Histone arginine methylation keeps RUNX1 target genes in an intermediate state.Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesisDecreased platelet expression of myosin regulatory light chain polypeptide (MYL9) and other genes with platelet dysfunction and CBFA2/RUNX1 mutation: insights from platelet expression profiling.Human phenotypes associated with GATA-1 mutations.MegakaryopoiesisThrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiencyMechanism of platelet factor 4 (PF4) deficiency with RUNX1 haplodeficiency: RUNX1 is a transcriptional regulator of PF4.Platelet protein kinase C-theta deficiency with human RUNX1 mutation: PRKCQ is a transcriptional target of RUNX1.Inherited thrombocytopenias: an approach to diagnosis and management.Novel insights into the genetic controls of primitive and definitive hematopoiesis from zebrafish modelsRUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins.Development of hairy cell leukemia in familial platelet disorder with predisposition to acute myeloid leukemia.
P2860
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P2860
AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@ast
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@en
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@nl
type
label
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@ast
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@en
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@nl
prefLabel
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@ast
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@en
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@nl
P2093
P356
P1433
P1476
AML-1 is required for megakary ...... cells in adult hematopoiesis.
@en
P2093
Hisamaru Hirai
Ieharu Yamazaki
Kinuko Mitani
Mineo Kurokawa
Sachiko Seo
Seishi Ogawa
Shigeru Chiba
Takashi Asai
Tetsuya Yamagata
Toshiki Saito
P2888
P304
P356
10.1038/NM997
P407
P577
2004-02-15T00:00:00Z