PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01.
about
CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stressPutting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?Two 4N cell-cycle arrests contribute to cisplatin-resistanceCHIP regulates AKT/FoxO/Bim signaling in MCF7 and MCF10A cellsFoxO3a negatively regulates nerve growth factor-induced neuronal differentiation through inhibiting the expression of neurochondrin in PC12 cellsAurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells.Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis.The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.Expression of PUMA in Follicular Granulosa Cells Regulated by FoxO1 Activation During Oxidative Stress.Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growthmTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.Caspase-9 mediates Puma activation in UCN-01-induced apoptosis.Crizotinib induces PUMA-dependent apoptosis in colon cancer cells.PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells.Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.Role of apoptosis in colon cancer biology, therapy, and preventionProapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cellsHuman endometrial mesenchymal stem cells exhibit intrinsic anti-tumor properties on human epithelial ovarian cancer cells.EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis.Idelalisib induces PUMA-dependent apoptosis in colon cancer cells.Pazopanib, a novel multi-kinase inhibitor, shows potent antitumor activity in colon cancer through PUMA-mediated apoptosis.Inhibition of AKT/FoxO3a signaling induced PUMA expression in response to p53-independent cytotoxic effects of H1: A derivative of tetrandrine.Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity.Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells.Reducing protein regulator of cytokinesis 1 as a prospective therapy for hepatocellular carcinoma.PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors.MEK inhibitors induce apoptosis via FoxO3a-dependent PUMA induction in colorectal cancer cellsInhibition of kinesin family member 20B sensitizes hepatocellular carcinoma cell to microtubule-targeting agents by blocking cytokinesis
P2860
Q24339500-02348A49-F656-4A37-AE9F-0145D513A31EQ28085240-DFA4E065-BCE0-43E6-AA67-1580A8055CF1Q28485896-1A5F654E-009E-43C2-BAA4-5065EF67F39FQ28537854-08335CF1-B67D-4AE7-907D-9C40CD1428BBQ28574521-92BCA310-6D9D-4D13-BF9C-FB8625B593ABQ33579079-5A930A7B-6A2C-4773-BAE0-6B7CDA1BEE72Q33838524-04A0C912-C5D3-4C69-8536-C408219C27C0Q34389359-5343277A-0854-418D-9308-007442AAB726Q35853145-ABD58B67-F8DC-489D-BC23-25B8CF9577BCQ35928707-6C4EBE2D-9E55-4A57-A418-B4D06312CE05Q36156993-1CAC8FAD-6ED0-47CF-845C-D06EC80FF4BCQ36291178-3D98746B-08BB-4F3F-A885-280169F1828CQ36836921-2A2A14B8-38E7-4531-BC7C-3404391825ACQ37073648-3F53909C-22FC-4E9F-8A24-3BF0D5C7CDF8Q37296982-7EC02044-C57C-45DB-BDDC-B56440CBC03CQ37331465-5768D408-E7E6-4229-9AF4-814CB3DA6F19Q37408752-6DA7B3AF-E163-4C1D-9F48-694B93D33050Q37414261-E62910F0-27D2-4FFD-9173-4FC1586B9417Q37636628-FDDA60D0-F92E-4EE3-8279-D6076E39563FQ37701548-B6A2AE6E-033A-4257-8A8D-05A4B8C39309Q37709464-548CBF39-5B87-464F-975E-D4B125C4DC6FQ38884553-01B81EEA-C6E7-4811-970A-B07CD16977B6Q41023161-CB018B1D-B56D-4752-9543-D9694BAFC4BBQ41987166-38FDE67D-7628-4BF0-9B3E-D8B63C83CC51Q51136478-26CEF986-F02D-4DC9-950D-0EA92C4C19DAQ53684279-E0E459F4-604A-42B3-8F2A-FB231B55EDD4Q55309918-65AEBD05-CC44-4228-95FE-FABA3279071BQ58760429-BE8B6497-665D-4114-AFBF-3490118B661EQ58783840-FECC38DA-34FC-46B0-AA28-F4682A392C43
P2860
PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@ast
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@en
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@nl
type
label
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@ast
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@en
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@nl
prefLabel
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@ast
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@en
PUMA induction by FoxO3a media ...... range kinase inhibitor UCN-01.
@nl
P2093
P2860
P1476
PUMA induction by FoxO3a media ...... -range kinase inhibitor UCN-01
@en
P2093
Crissy Dudgeon
Quanhong Sun
Xiameng Sun
P2860
P304
P356
10.1158/1535-7163.MCT-10-0635
P577
2010-10-26T00:00:00Z