Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions - Wikidata - awgldk - TriplyDB

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

http://www.wikidata.org/entity/Q34304263

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Genomic diversity of colorectal cancer: Changing landscape and emerging targets Tumor evolution and intratumor heterogeneity in colorectal carcinoma: insights from comparative genomic profiling of primary tumors and matched metastases HER2 activating mutations are targets for colorectal cancer treatment Molecular predictive markers in tumors of the gastrointestinal tract Mouse models of colorectal cancer as preclinical models Colorectal Cancer Classification and Cell Heterogeneity: A Systems Oncology Approach Colorectal Cancer Genetic Heterogeneity Delineated by Multi-Region Sequencing DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.Indel variant analysis of short-read sequencing data with Scalpel.PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases.Detection of COPB2 as a KRAS synthetic lethal partner through integration of functional genomics screens.High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.HIF-2α mediates hypoxia-induced LIF expression in human colorectal cancer cells.Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.Transcriptome analysis of paired primary colorectal carcinoma and liver metastases reveals fusion transcripts and similar gene expression profiles in primary carcinoma and liver metastases.Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection.Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer Clonal status of actionable driver events and the timing of mutational processes in cancer evolution.Genome-wide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels.Prognostic significance of K-Ras mutation rate in metastatic colorectal cancer patients.Tissue Metabonomic Phenotyping for Diagnosis and Prognosis of Human Colorectal Cancer.Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations.GUCY2C ligand replacement to prevent colorectal cancer.Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients.Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology.Comparative genomic analysis of primary tumors and metastases in breast cancer.Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases Institutional implementation of clinical tumor profiling on an unselected cancer population.High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer.Individualised multiplexed circulating tumour DNA assays for monitoring of tumour presence in patients after colorectal cancer surgery.Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer.Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer.ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib.Comparative profiling between primary colorectal carcinomas and metastases identifies heterogeneity on drug resistance.Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale.Transcriptome analysis in primary colorectal cancer tissues from patients with and without liver metastases using next-generation sequencing.Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer.

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Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

http://www.wikidata.org/entity/Q34304263

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Comparative sequencing analysi ...... atic colorectal cancer lesions

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Comparative sequencing analysi ...... atic colorectal cancer lesions

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Comparative sequencing analysi ...... atic colorectal cancer lesions

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Comparative sequencing analysi ...... atic colorectal cancer lesions

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Andrea Cercek

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P2860

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Comprehensive molecular characterization of human colon and rectal cancer

Fast and accurate short read alignment with Burrows-Wheeler transform

A genetic model for colorectal tumorigenesis

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

The Sequence Alignment/Map format and SAMtools

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

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