Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement.
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The Knowns Unknowns: Exploring the Homologous Recombination Repair Pathway in Toxoplasma gondiiNucleases in homologous recombination as targets for cancer therapyRPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage responseHrq1 facilitates nucleotide excision repair of DNA damage induced by 4-nitroquinoline-1-oxide and cisplatin in Saccharomyces cerevisiae.The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) PhenotypeReappearance from Obscurity: Mammalian Rad52 in Homologous RecombinationAssociation of a functional RAD52 genetic variant locating in a miRNA binding site with risk of HBV-related hepatocellular carcinomaA RAD52 genetic variant located in a miRNA binding site is associated with glioma risk in Han ChineseDouble-strand break repair and colorectal cancer: gene variants within 3' UTRs and microRNAs binding as modulators of cancer risk and clinical outcomeFission yeast Rad52 phosphorylation restrains error prone recombination pathwaysDrugging the Cancers Addicted to DNA Repair.Evolution of a strategy for preparing bioactive small molecules by sequential multicomponent assembly processes, cyclizations, and diversificationThe 12p13.33/RAD52 locus and genetic susceptibility to squamous cell cancers of upper aerodigestive tractCurcumin-Mediated HDAC Inhibition Suppresses the DNA Damage Response and Contributes to Increased DNA Damage Sensitivity.Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers.Deciphering the BRCA1 Tumor Suppressor Network.Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors.FANCD2 influences replication fork processes and genome stability in response to clustered DSBs.Identification of an SCLC susceptibility rs7963551 genetic polymorphism in a previously GWAS-identified 12p13.33 RAD52 lung cancer risk locus in the Chinese population.Functional characterization of RAD52 as a lung cancer susceptibility gene in the 12p13.33 locusHuman RAD52 interactions with replication protein A and the RAD51 presynaptic complex.Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cellsMammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.microRNAs in cancer cell response to ionizing radiation.Targeting homologous recombination-mediated DNA repair in cancer.Mediators of homologous DNA pairing.Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair.53BP1 fosters fidelity of homology-directed DNA repair.Unravelling the biology of SCLC: implications for therapy.The Shu complex is a conserved regulator of homologous recombination.DNA annealing by Redβ is insufficient for homologous recombination and the additional requirements involve intra- and inter-molecular interactions.A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer.The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining.Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair.Human RAD52 - a novel player in DNA repair in cancer and immunodeficiencyRAD52 gene polymorphisms are associated with risk of colorectal cancer in a Chinese Han population.Increased single-strand annealing rather than non-homologous end-joining predicts hereditary ovarian carcinoma.Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break.
P2860
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P2860
Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Molecular pathways: understand ...... n for therapeutic advancement.
@ast
Molecular pathways: understand ...... n for therapeutic advancement.
@en
Molecular pathways: understand ...... n for therapeutic advancement.
@nl
type
label
Molecular pathways: understand ...... n for therapeutic advancement.
@ast
Molecular pathways: understand ...... n for therapeutic advancement.
@en
Molecular pathways: understand ...... n for therapeutic advancement.
@nl
prefLabel
Molecular pathways: understand ...... n for therapeutic advancement.
@ast
Molecular pathways: understand ...... n for therapeutic advancement.
@en
Molecular pathways: understand ...... n for therapeutic advancement.
@nl
P2860
P1476
Molecular pathways: understand ...... n for therapeutic advancement.
@en
P2093
Benjamin H Lok
Simon N Powell
P2860
P304
P356
10.1158/1078-0432.CCR-11-3150
P407
P577
2012-10-15T00:00:00Z