eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay.
about
Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein coreProteins associated with the exon junction complex also control the alternative splicing of apoptotic regulatorsThe cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexusBinding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decayeIF4G is required for the pioneer round of translation in mammalian cellsHuman DDX3 functions in translation and interacts with the translation initiation factor eIF3Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translationStimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation.mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay.DEAD-box proteins as RNA helicases and chaperonesATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwindingSplicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex componentsA GFP-based reporter system to monitor nonsense-mediated mRNA decayDEAD-box helicases as integrators of RNA, nucleotide and protein bindingPost-transcriptional regulation in corticogenesis: how RNA-binding proteins help build the brainThe Clothes Make the mRNA: Past and Present Trends in mRNP FashionCrystal structure of the human eIF4AIII-CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domainAn interaction between two RNA binding proteins, Nab2 and Pub1, links mRNA processing/export and mRNA stability.Nonsense-mediated mRNA decay in humans at a glanceNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryThe nuclear experience of CPEB: implications for RNA processing and translational control.Eukaryotic initiation factor 4a3 is a selenium-regulated RNA-binding protein that selectively inhibits selenocysteine incorporationExpression of the core exon-junction complex factor eukaryotic initiation factor 4A3 is increased during spatial exploration and striatally-mediated learningIdentification of a signature motif for the eIF4a3-SECIS interactionA proteomic comparison of immature and mature mouse gonadotrophs reveals novel differentially expressed nuclear proteins that regulate gonadotropin gene transcription and RNA splicingInhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A through Eukaryotic Initiation Factor 4AIIIA paired-end sequencing strategy to map the complex landscape of transcription initiation.Eif4a3 is required for accurate splicing of the Xenopus laevis ryanodine receptor pre-mRNAMLN51 stimulates the RNA-helicase activity of eIF4AIII.Selective pharmacological targeting of a DEAD box RNA helicase.Splicing of U12-type introns deposits an exon junction complex competent to induce nonsense-mediated mRNA decay.Control of VP16 translation by the herpes simplex virus type 1 immediate-early protein ICP27.Transcriptomic responses to salinity stress in invasive and native blue mussels (genus Mytilus).Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombeRetention of spliceosomal components along ligated exons ensures efficient removal of multiple intronsThe nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.Eukaryotic initiation factor 4F: a vulnerability of tumor cells.Dual roles for the Mss116 cofactor during splicing of the ai5γ group II intron.The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript.
P2860
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P2860
eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay.
description
2004 nî lūn-bûn
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2004 թուականի Մարտին հրատարակուած գիտական յօդուած
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2004 թվականի մարտին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
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2004年论文
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name
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@ast
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@en
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@nl
type
label
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@ast
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@en
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@nl
prefLabel
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@ast
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@en
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@nl
P2093
P356
P1476
eIF4AIII binds spliced mRNA in ...... l for nonsense-mediated decay.
@en
P2093
Melissa J Moore
Thomas Ø Tange
Toshiharu Shibuya
P2888
P304
P356
10.1038/NSMB750
P577
2004-03-21T00:00:00Z