Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells. - Wikidata - awgldk - TriplyDB

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.

http://www.wikidata.org/entity/Q34313686

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Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors Practical aspects of NGS-based pathways analysis for personalized cancer science and medicine Cancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer Medicine Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics Databases and web tools for cancer genomics study In vitro and in vivo models for analysis of resistance to anticancer molecular therapies Apoptotic agents The proteomic landscape of triple-negative breast cancer.Therapeutic targeting of cancers with loss of PTEN function.Biological Networks for Cancer Candidate Biomarkers Discovery Approaches to modernize the combination drug development paradigm Toward precision medicine of breast cancer SETD2: an epigenetic modifier with tumor suppressor functionality Using Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer Therapy Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination Leveraging systems biology approaches in clinical pharmacology Analysis of individual protein regions provides novel insights on cancer pharmacogenomics Integrated analysis of transcriptome in cancer patient-derived xenografts Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling A Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning Predictions HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B A Copula Based Approach for Design of Multivariate Random Forests for Drug Sensitivity Prediction Integrating Domain Specific Knowledge and Network Analysis to Predict Drug Sensitivity of Cancer Cell Lines Integrative network modeling approaches to personalized cancer medicine Inferences of drug responses in cancer cells from cancer genomic features and compound chemical and therapeutic properties Repositioning approved drugs for the treatment of problematic cancers using a screening approach.COSMIC: exploring the world's knowledge of somatic mutations in human cancer What's that gene (or protein)? Online resources for exploring functions of genes, transcripts, and proteins.A community effort to assess and improve drug sensitivity prediction algorithms.NCI-60 Cell Line Screening: A Radical Departure in its Time.mutLBSgeneDB: mutated ligand binding site gene DataBase.The 2013 Nucleic Acids Research Database Issue and the online molecular biology database collection.Association of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia.PiHelper: an open source framework for drug-target and antibody-target data.An unbiased metric of antiproliferative drug effect in vitro.DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data.MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cells How Consistent are Publicly Reported Cytotoxicity Data? Large-Scale Statistical Analysis of the Concordance of Public Independent Cytotoxicity Measurements.

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Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.

http://www.wikidata.org/entity/Q34313686

description

2012 nî lūn-bûn

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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի նոյեմբերին հրատարակված գիտական հոդված

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Genomics of Drug Sensitivity i ...... ker discovery in cancer cells.

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Genomics of Drug Sensitivity in Cancer

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Genomics of Drug Sensitivity in Cancer

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Genomics of Drug Sensitivity i ...... ker discovery in cancer cells.

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Nucleic Acids Research

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Cyril Benes

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Daniel A Haber

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Dave Beare

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Elena J Edelman

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I Richard Thompson

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Jorge Soares

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Mathew J Garnett

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Patricia Greninger

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Simon Forbes

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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.

Reorganizing the protein space at the Universal Protein Resource (UniProt)

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Systematic identification of genomic markers of drug sensitivity in cancer cells

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.

Exploring the genomes of cancer cells: progress and promise.

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D955-61

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10.1093/NAR/GKS1111

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Database issue

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41

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Ultan McDermott

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Michael Stratton

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2012-11-23T00:00:00Z

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233770705

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23180760

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