Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.
about
PTEN function: how normal cells control it and tumour cells lose itEpigenetics of colorectal cancerMarkers of resistance to anti-EGFR therapy in colorectal cancerThe PI3K pathway as drug target in human cancerMicroRNAs as growth regulators, their function and biomarker status in colorectal cancerFocus on PTEN RegulationPersonalized treatment for advanced colorectal cancer: KRAS and beyondPrimary and acquired resistance to EGFR-targeted therapies in colorectal cancer: impact on future treatment strategiesTherapeutic targeting of cancers with loss of PTEN function.Immunotherapy in human colorectal cancer: Challenges and prospectiveMechanisms of resistance to anti-EGFR therapy in colorectal cancerGenetics and Genetic Biomarkers in Sporadic Colorectal CancerShank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells.Immunophenotype and molecular characterisation of adenocarcinoma of the small intestine.Optimization of a pentaplex panel for MSI analysis without control DNA in a Brazilian population: correlation with ancestry markers.Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study: associations with clinicopathological and dietary factors.Clement Richard Boland, Jr., MD: a conversation with the editor. Interview by William Clifford RobertsRAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cellsDNA methylation in endometrial cancerMetastasis-associated protein 1/histone deacetylase 4-nucleosome remodeling and deacetylase complex regulates phosphatase and tensin homolog gene expression and function.LOH at 6q and 10q in fractionated circulating DNA of ovarian cancer patients is predictive for tumor cell spread and overall survival.Indole-3-carbinol prevents PTEN loss in cervical cancer in vivoMicrosatellite instability in colorectal cancer-the stable evidence.PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancerFISH analysis of PTEN in endometrial carcinoma. Comparison with SNP arrays and MLPA.Beyond KRAS: perspectives on new potential markers of intrinsic and acquired resistance to epidermal growth factor receptor inhibitors in metastatic colorectal cancerCan we accurately report PTEN status in advanced colorectal cancer?Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy.Intestinal epithelial-specific PTEN inactivation results in tumor formation.A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.Epigenetics could explain some Moroccan population colorectal cancers peculiarities: microsatellite instability pathway exploration.A comprehensive analysis of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) loss in colorectal cancer.Molecular pathways: microsatellite instability in colorectal cancer: prognostic, predictive, and therapeutic implicationsMulti-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel BiomarkersMiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer.Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing.PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer.The complexity of PTEN: mutation, marker and potential target for therapeutic intervention.Identification of a tumour suppressor network opposing nuclear Akt functionPTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study
P2860
Q24528114-D77A7477-8F40-49DF-B584-6C46593A6408Q24598045-0F4E3DC9-A2F2-4251-A9A0-EE274881842DQ24598640-05A2CC34-CF23-4A59-8EA2-C7EC2E935EEFQ24632283-8D715ACB-082B-40D3-85DC-BF1E6C8A72FEQ26775610-0821C330-A3CC-4901-9E6A-FC184B374077Q26797287-A73119A6-D6D9-44CB-9077-BA13AD1118C6Q26822817-4DDE6527-1887-4975-BEB4-2A43E548EDBDQ27015224-0B74DD29-2A1C-49C0-976B-6DC8E5DEC9C3Q27852764-4A9B1CEC-D61C-4886-9085-F9B40B5D494AQ28068788-4C4C9ECB-A332-413A-997B-ECD207A6A628Q28074073-C7B4425C-51B9-4EC9-A9B6-299F94930D13Q28084346-F3FFB2D3-0287-4FA6-9AC0-C6C26610F222Q30494717-2A493C65-1999-428C-B531-5C65E1A8218AQ33620113-A6C98316-A1E1-4761-B97D-BC43F4588B9EQ33765195-C20755C9-AF37-46D9-B3E7-6FA0074B4050Q33865287-B38AEAD4-1956-4526-AFC2-994F3673CDA8Q33945019-6B08899A-E9C0-427F-8F2B-9E4A802DF894Q34117879-58DA3937-E0F1-46D9-A851-A122E81D670CQ34195371-C0C0BD6E-244D-46D4-8D1E-F5CD60A67DBFQ34281765-EA02D731-4127-4780-B31D-4A0BBD403C5CQ34360216-48E03351-476A-4ED2-84FF-67F28665F4DBQ34572332-9ABF5350-551C-4D82-B6CC-C4E3D5B92D62Q34616565-9498FD2F-AD14-4639-91E9-F517BDBEA646Q34778769-806C60AC-1199-4EA3-AE4A-1D699B9EDB62Q34805622-6BC610DB-29C3-4740-BEE8-00C976DC74A8Q35076220-3D956505-322A-4954-BFA9-DC11DC0463CBQ35101357-85B2685A-CCA7-4D1A-A132-5B2F6199B3C5Q35233751-0DE2B367-5143-4B66-AA5C-5F2D712F0086Q35562094-CD9D5A25-DDE4-4AC5-BE7E-D7BD4D07D505Q35584153-033EC8D9-E67D-4EC3-AA1F-157B44A3D8A0Q35770433-7CE02E19-1146-465F-9656-F32E195BCEC0Q35810031-A94E4067-B301-4A36-87EF-628A62711497Q35836592-15AAF8F7-CA28-477E-BA4A-4924CD252ED7Q35871650-8DC31C79-D398-4B38-874D-808B0B95973AQ35910713-ACAA8447-0E53-4A08-8E42-B42927B3EBACQ35926060-C77735E8-ECF2-41D0-9E74-CF22D3E414DCQ35953893-FA53EFC8-BD40-4ACA-861F-EADA87699AAEQ35976355-9FE0CEBD-0B5B-4A35-AF31-44FA629FF4AAQ35991130-CFA68E14-D98A-4256-9A77-9ED1BE68B542Q36050773-61272F34-2951-4572-BD54-2AB6B28557E0
P2860
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@ast
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@en
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@nl
type
label
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@ast
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@en
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@nl
prefLabel
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@ast
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@en
Frequent inactivation of PTEN ...... h sporadic colorectal cancers.
@nl
P2093
P1433
P1476
Frequent inactivation of PTEN ...... gh sporadic colorectal cancers
@en
P2093
C Richard Boland
Carolyn Compton
Christian N Arnold
Donna Niedzwiecki
Jeannette M Dowell
John M Carethers
Linda Wasserman
Monica M Bertagnolli
Robert J Mayer
P304
P356
10.1158/0008-5472.CAN-2401-2
P407
P50
P577
2004-05-01T00:00:00Z