Selective antagonist for the cerebellar granule cell-specific gamma-aminobutyric acid type A receptor.
about
Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning.Methods for recording and measuring tonic GABAA receptor-mediated inhibitionEffects of gamma-HCH and delta-HCH on human recombinant GABA(A) receptors: dependence on GABA(A) receptor subunit combinationProton sensitivity of rat cerebellar granule cell GABAA receptors: dependence on neuronal developmentEffects of GABA(A) receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositionsRat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinitiesContributions of the GABAA receptor alpha6 subunit to phasic and tonic inhibition revealed by a naturally occurring polymorphism in the alpha6 geneDynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integrationTheta-bursts induce a shift in reversal potentials for GABA-A receptor-mediated postsynaptic currents in rat hippocampal CA1 neurons.Opposite actions of alcohol on tonic GABA(A) receptor currents mediated by nNOS and PKC activity.ENaC-expressing neurons in the sensory circumventricular organs become c-Fos activated following systemic sodium changes.GABAA alpha6-containing receptors are selectively compromised in cerebellar granule cells of the ataxic mouse, stargazer.Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A receptors.Extrasynaptic α6 subunit-containing GABAA receptors modulate excitability in turtle spinal motoneurons.Specific inhibition of the plasmodial surface anion channel by dantroleneA 17beta-derivative of allopregnanolone is a neurosteroid antagonist at a cerebellar subpopulation of GABA A receptors with nanomolar affinity.Unexpected extra-renal effects of loop diuretics in the preterm neonateAssessment of subunit-dependent direct gating and allosteric modulatory effects of carisoprodol at GABA(A) receptors.NSAIDs modulate GABA-activated currents via Ca(2+)-activated Cl(-) channels in rat dorsal root ganglion neuronsSynthesis of GABAA receptor agonists and evaluation of their alpha-subunit selectivity and orientation in the GABA binding siteWeaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome.Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited statesPresynaptic actions of propofol enhance inhibitory synaptic transmission in isolated solitary tract nucleus neurons.Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.Primate cerebellar granule cells exhibit a tonic GABAAR conductance that is not affected by alcohol: a possible cellular substrate of the low level of response phenotype.Furosemide depresses the presynaptic fiber volley and modifies frequency-dependent axonal excitability in rat hippocampus.Alcohol Suppresses Tonic GABAA Receptor Currents in Cerebellar Granule Cells in the Prairie Vole: A Neural Signature of High-Alcohol-Consuming Genotypes.The cerebellar GABAAR α6-R100Q polymorphism alters ligand binding in outbred Sprague-Dawley rats in a similar manner as in selectively bred AT and ANT rats.Pre- and postsynaptic modulation of monosynaptic reflex by GABAA receptors on turtle spinal cord.The K+-Cl cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus.Methylmercury differentially affects GABA(A) receptor-mediated spontaneous IPSCs in Purkinje and granule cells of rat cerebellar slices.Tonic inhibition sets the state of excitability in olfactory bulb granule cells.Methylmercury induces an initial increase in GABA-evoked currents in Xenopus oocytes expressing α1 and α6 subunit-containing GABAA receptors.Time-invariant feed-forward inhibition of Purkinje cells in the cerebellar cortex in vivo.Cerebellar α6 subunit-containing GABAA receptors: A novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor
P2860
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P2860
Selective antagonist for the cerebellar granule cell-specific gamma-aminobutyric acid type A receptor.
description
1995 nî lūn-bûn
@nan
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Selective antagonist for the c ...... obutyric acid type A receptor.
@ast
Selective antagonist for the c ...... obutyric acid type A receptor.
@en
Selective antagonist for the c ...... obutyric acid type A receptor.
@nl
type
label
Selective antagonist for the c ...... obutyric acid type A receptor.
@ast
Selective antagonist for the c ...... obutyric acid type A receptor.
@en
Selective antagonist for the c ...... obutyric acid type A receptor.
@nl
prefLabel
Selective antagonist for the c ...... obutyric acid type A receptor.
@ast
Selective antagonist for the c ...... obutyric acid type A receptor.
@en
Selective antagonist for the c ...... obutyric acid type A receptor.
@nl
P2093
P1476
Selective antagonist for the c ...... obutyric acid type A receptor.
@en
P2093
P304
P577
1995-02-01T00:00:00Z