Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.
about
Catamenial Epilepsy: Discovery of an Extrasynaptic Molecular Mechanism for Targeted TherapyThe role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disordersAllopregnanolone as a mediator of affective switching in reproductive mood disordersNeurosteroids and their role in sex-specific epilepsiesThe neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gatingPaired-Associative Stimulation-Induced Long-term Potentiation-Like Motor Cortex Plasticity in Healthy Adolescents.Altered GABAergic Signaling in Brain Disease at Various Stages of Life.Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies.Variation in AKR1C3, which encodes the neuroactive steroid synthetic enzyme 3α-HSD type 2 (17β-HSD type 5), moderates the subjective effects of alcoholPerimenstrual-like hormonal regulation of extrasynaptic δ-containing GABAA receptors mediating tonic inhibition and neurosteroid sensitivity.Neurosteroid biosynthesis downregulation and changes in GABAA receptor subunit composition: A biomarker axis in stress-induced cognitive and emotional impairment.Glutamate, GABA, and glutamine are synchronously upregulated in the mouse lateral septum during the postpartum period.Synaptic-type α1β2γ2L GABAA receptors produce large persistent currents in the presence of ambient GABA and anesthetic drugs.Antiseizure Activity of Midazolam in Mice Lacking δ-Subunit Extrasynaptic GABA(A) ReceptorsPhosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABAA receptor function.Midazolam as an anticonvulsant antidote for organophosphate intoxication--A pharmacotherapeutic appraisalThe 5α-reductase inhibitor finasteride is not associated with alterations in sleep spindles in men referred for polysomnography.Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research.Neurosteroid Structure-Activity Relationships for Functional Activation of Extrasynaptic δGABA(A) Receptors.Zinc Selectively Blocks Neurosteroid-Sensitive Extrasynaptic δGABAA Receptors in the Hippocampus.Sex differences in the anticonvulsant activity of neurosteroidsSex differences in hippocampal area CA3 pyramidal cells.Clinical Potential of Neurosteroids for CNS Disorders.GABA pharmacology: the search for analgesics.GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system.Progesterone and its metabolites as therapeutic targets in psychiatric disorders.Current and Future Issues in the Development of Spinal Agents for the Management of Pain.Inhibitory neurotransmission regulates vagal efferent activity and gastric motility.Neurosteroids for the potential protection of humans against organophosphate toxicity.Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes.A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome.Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator.Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones.The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: effects of estradiol and progesterone addback.Self-administration of progesterone and synthetic neuroactive steroids by male rhesus monkeys.GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy.Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichment on δ-Containing GABAA Receptor Expression in the Cerebellum of Subjects with Alcohol Use Disorders (AUD).Changes in stress-stimulated allopregnanolone levels induced by neonatal estradiol treatment are associated with enhanced dopamine release in adult female rats: reversal by progesterone administration.Dynamic Adaptation in Neurosteroid Networks in Response to Alcohol.Randomized, double-blind, placebo-controlled phase 2 study of ganaxolone as add-on therapy in adults with uncontrolled partial-onset seizures.
P2860
Q26752707-2F8FED35-409F-4024-AB39-5344231992F8Q26851296-BAA40952-10B3-478C-BA26-853DDEE033E2Q26866177-8162C7CA-631E-41BD-B216-A511ED4AD20FQ27026373-10F2F66A-9F69-40C4-B5CD-D9A384715905Q30367021-58626601-DF71-4498-8CDE-3EC8E90E730BQ33734861-EB5F7911-0249-4B7E-89CD-7F863A07FEE8Q33854558-05117FDB-1EAB-4723-B261-822289497E61Q34054035-97DBE217-B653-48A0-BEC1-CEC0525DF651Q34054066-9259F34A-8BD6-44A6-B81C-A3D0A61E0341Q34383389-2984791D-745C-4275-A68D-F9AB518263B2Q34556039-8ED6CC61-C4F9-485A-8B9E-1ADBC59E5C97Q35032616-19FC619A-1D06-49CA-B573-DEA5508BDF20Q35531843-E1BBFDFE-A163-44E8-A567-24D5A2E4FA7AQ35600228-52F48ABD-D14E-463E-A91A-DDCBB6B46998Q35629077-05F18A94-CAC3-4EDC-BE0D-8BADEF6A5EEEQ35688988-620518BB-9646-4A94-9FD2-CFD18A671CD9Q36479550-8FFE048E-9366-467D-BBE0-1979FAC3D20FQ36626032-44DAF569-A352-487B-8868-2ED4D95A5DA6Q36733535-00ECA7B5-8226-4571-BA9E-58EC1740A243Q37147577-839BBF1F-FD29-4F8C-9CA7-74F41B565140Q37432122-5B253303-DD77-4D97-986B-D010EEE66859Q37432353-D53D0788-7BED-49FB-A155-651C43AE9402Q37643528-7D13BD13-00FD-46BE-81E6-49114440E897Q38188497-BF791DAE-87AB-46B2-82F1-EEC60582152EQ38195925-25DBEE99-5F9E-4E57-8893-205449C282FFQ38198091-C839A98A-33BB-44A0-A169-1224D536AB47Q38727831-2F934758-90F3-46CD-A931-CF427E9AFF01Q38865388-A679ECB9-0A48-4134-9A67-A44232970629Q38906587-57B4C9F1-F7EA-4D54-A0B0-3101D4AE1C65Q41108241-EFE2D9F5-5D33-4D35-B5FC-5C17604275ADQ41215871-15FB3F9B-6869-48BE-8200-54C168C5E688Q41258644-8CB4B6C3-8F19-4972-9770-ED1AB95EA320Q41628434-6B705AF1-2844-44BC-A81F-BF3699C11BEEQ41687556-6566D628-8016-42CE-B26D-ED26FB2B56FFQ41884732-499EE7B9-A027-4543-92E5-BAB717803A32Q43039942-2806AFE9-3126-4C3B-AD75-3DCDFF8704ECQ47108980-294CB8C1-C956-45D3-9B87-4545D29A7DA4Q47246883-257C36D4-3CEC-49B9-A76C-7E34C6FDC810Q47306333-5ECD1C8F-88F1-4787-A7EB-DE3287EC6449Q47326787-51E0F908-8A24-4595-94A5-E3EE9795010D
P2860
Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Neurosteroid interactions with ...... neuronal network excitability.
@en
Neurosteroid interactions with ...... neuronal network excitability.
@nl
type
label
Neurosteroid interactions with ...... neuronal network excitability.
@en
Neurosteroid interactions with ...... neuronal network excitability.
@nl
prefLabel
Neurosteroid interactions with ...... neuronal network excitability.
@en
Neurosteroid interactions with ...... neuronal network excitability.
@nl
P2860
P1433
P1476
Neurosteroid interactions with ...... neuronal network excitability.
@en
P2093
Chase Matthew Carver
P2860
P2888
P304
P356
10.1007/S00213-013-3276-5
P50
P577
2013-09-27T00:00:00Z