Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice. - Wikidata - awgldk - TriplyDB

Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice.

Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice.

http://www.wikidata.org/entity/Q34321178

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Dysregulation of skeletal muscle protein metabolism by alcohol How to explain exercise-induced phenotype from molecular data: rethink and reconstruction based on AMPK and mTOR signaling.Disruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice.Interdependence of muscle atrophy and bone loss induced by mechanical unloading Salutary effect of aurintricarboxylic acid on endotoxin- and sepsis-induced changes in muscle protein synthesis and inflammation Alcoholic cardiomyopathy: pathophysiologic insights REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1: responses to aging, immobilization, and remobilization.Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction.A dietary supplementation with leucine and antioxidants is capable to accelerate muscle mass recovery after immobilization in adult rats Time-Course of Muscle Mass Loss, Damage, and Proteolysis in Gastrocnemius following Unloading and Reloading: Implications in Chronic Diseases.Slow recovery of the impaired fatigue resistance in postunloading mouse soleus muscle corresponding to decreased mitochondrial function and a compensatory increase in type I slow fibers.The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb.Direct central nervous system effect of alcohol alters synthesis and degradation of skeletal muscle protein.Aging accentuates alcohol-induced decrease in protein synthesis in gastrocnemius.Ribosome biogenesis: emerging evidence for a central role in the regulation of skeletal muscle mass.Disuse-induced muscle wasting.Marginal dietary zinc deprivation augments sepsis-induced alterations in skeletal muscle TNF-α but not protein synthesis.Chronic alcohol consumption disrupts myocardial protein balance and function in aged, but not adult, female F344 rats.Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression.Nutritional strategies to counteract muscle atrophy caused by disuse and to improve recovery.Immune and metabolic responses in early and late sepsis during mild dietary zinc restriction.Decreased Whole-Body Fat Mass Produced by Chronic Alcohol Consumption is Associated with Activation of S6K1-Mediated Protein Synthesis and Increased Autophagy in Epididymal White Adipose Tissue.Simulated space radiation sensitizes bone but not muscle to the catabolic effects of mechanical unloading.Lysine suppresses myofibrillar protein degradation by regulating the autophagic-lysosomal system through phosphorylation of Akt in C2C12 cells.The worsening of tibialis anterior muscle atrophy during recovery post-immobilization correlates with enhanced connective tissue area, proteolysis, and apoptosis.Short- and Long-Term Hindlimb Immobilization and Reloading: Profile of Epigenetic Events in Gastrocnemius.PGC-1α over-expression suppresses the skeletal muscle atrophy and myofiber-type composition during hindlimb unloading.Restorative Mechanisms Regulating Protein Balance in Skeletal Muscle During Recovery From Sepsis.Akt-dependent and Akt-independent pathways are involved in protein synthesis activation during reloading of disused soleus muscle.Repressors of mTORC1 act to blunt the anabolic response to feeding in the soleus muscle of a cast-immobilized mouse hindlimb

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Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice.

http://www.wikidata.org/entity/Q34321178

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年学术文章

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2012年學術文章

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name

Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Delayed recovery of skeletal m ...... ion in mTOR heterozygous mice.

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Abid A Kazi

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Charles H Lang

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Ly Hong-Brown

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Susan M Lang

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P2860

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

Distinct protein degradation profiles are induced by different disuse models of skeletal muscle atrophy

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