Binding of the herpes simplex virus major regulatory protein to viral DNA.
about
Temporal gene regulation of the channel catfish virus (Ictalurid herpesvirus 1).Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localizeRole of the IE62 consensus binding site in transactivation by the varicella-zoster virus IE62 proteinRepression of the herpes simplex virus 1 alpha 4 gene by its gene product (ICP4) within the context of the viral genome is conditioned by the distance and stereoaxial alignment of the ICP4 DNA binding site relative to the TATA boxThe promoter and transcriptional unit of a novel herpes simplex virus 1 alpha gene are contained in, and encode a protein in frame with, the open reading frame of the alpha 22 geneRole of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication.Repression of the alpha0 gene by ICP4 during a productive herpes simplex virus infection.Association of herpes simplex virus regulatory protein ICP22 with transcriptional complexes containing EAP, ICP4, RNA polymerase II, and viral DNA requires posttranslational modification by the U(L)13 proteinkinase.Nucleotides within both proximal and distal parts of the consensus sequence are important for specific DNA recognition by the herpes simplex virus regulatory protein ICP4.Repression of the herpes simplex virus 1 alpha 4 gene by its gene product occurs within the context of the viral genome and is associated with all three identified cognate sitesThe herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virusMitotic transcription repression in vivo in the absence of nucleosomal chromatin condensation.Analysis of the herpes simplex virus type 1 promoter controlling the expression of UL38, a true late gene involved in capsid assemblyDifferences in the poly(ADP-ribosyl)ation patterns of ICP4, the herpes simplex virus major regulatory protein, in infected cells and in isolated nuclei.The ICP4 binding sites in the herpes simplex virus type 1 glycoprotein D (gD) promoter are not essential for efficient gD transcription during virus infectionMutational analysis of the ICP4 binding sites in the 5' transcribed noncoding domains of the herpes simplex virus 1 UL 49.5 gamma 2 geneICP4, the major regulatory protein of herpes simplex virus, shares features common to GTP-binding proteins and is adenylated and guanylated.Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia.Site-specific binding of the human cytomegalovirus IE2 86-kilodalton protein to an early gene promoter.The initiator element in a herpes simplex virus type 1 late-gene promoter enhances activation by ICP4, resulting in abundant late-gene expressionPhysical and functional interactions between herpes simplex virus immediate-early proteins ICP4 and ICP27.Immediate-early expression of the herpes simplex virus type 1 ICP27 transcript is not critical for efficient replication in vitro or in vivoLocalization of a 34-amino-acid segment implicated in dimerization of the herpes simplex virus type 1 ICP4 polypeptide by a dimerization trap.The DNA binding domains of the varicella-zoster virus gene 62 and herpes simplex virus type 1 ICP4 transactivator proteins heterodimerize and bind to DNA.A truncated herpes simplex virus origin binding protein which contains the carboxyl terminal origin binding domain binds to the origin of replication but does not alter its conformation.Herpes simplex virus type 1 polypeptide ICP4 bends DNA.Purification of the DNA binding domain of herpes simplex virus type 1 immediate-early protein Vmw175 as a homodimer and extensive mutagenesis of its DNA recognition site.miRNAs Targeting ICP4 and Delivered to Susceptible Cells in Exosomes Block HSV-1 Replication in a Dose-Dependent Manner.
P2860
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P2860
Binding of the herpes simplex virus major regulatory protein to viral DNA.
description
1989 nî lūn-bûn
@nan
1989 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@ast
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@en
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@nl
type
label
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@ast
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@en
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@nl
prefLabel
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@ast
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@en
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@nl
P2860
P356
P1476
Binding of the herpes simplex virus major regulatory protein to viral DNA.
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.24.9808
P407
P577
1989-12-01T00:00:00Z