Physical and functional interactions between herpes simplex virus immediate-early proteins ICP4 and ICP27.
about
Association of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzymeHerpes simplex virus type 1 immediate-early protein ICP27 is required for efficient incorporation of ICP0 and ICP4 into virionsA viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responsesThe herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent neovascularization.The herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells.Analysis of the phosphorylation sites of herpes simplex virus type 1 regulatory protein ICP27.ICP27 recruits Aly/REF but not TAP/NXF1 to herpes simplex virus type 1 transcription sites although TAP/NXF1 is required for ICP27 export.Herpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathwaysProcessing of alpha-globin and ICP0 mRNA in cells infected with herpes simplex virus type 1 ICP27 mutants.Identification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1ICP22 and the UL13 protein kinase are both required for herpes simplex virus-induced modification of the large subunit of RNA polymerase II.Herpes simplex virus ICP27 activation of stress kinases JNK and p38.Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signalingUL54-null pseudorabies virus is attenuated in mice but productively infects cells in cultureAn early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.ICP27 interacts with the C-terminal domain of RNA polymerase II and facilitates its recruitment to herpes simplex virus 1 transcription sites, where it undergoes proteasomal degradation during infection.ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cellsDetermination of minimum herpes simplex virus type 1 components necessary to localize transcriptionally active DNA to ND10.Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1Mutational analysis of the herpes simplex virus type 1 ICP0 C3HC4 zinc ring finger reveals a requirement for ICP0 in the expression of the essential alpha27 gene.Interactions of the antizyme AtoC with regulatory elements of the Escherichia coli atoDAEB operon.Gene Expression Correlates with the Number of Herpes Viral Genomes Initiating Infection in Single Cells.Promoter- and cell-specific transcriptional transactivation by the Kaposi's sarcoma-associated herpesvirus ORF57/Mta protein.ICP4-induced miR-101 attenuates HSV-1 replicationThe co-chaperone BAG3 regulates Herpes Simplex Virus replication.Herpes simplex virus 1 gene expression is accelerated by inhibitors of histone deacetylases in rabbit skin cells infected with a mutant carrying a cDNA copy of the infected-cell protein no. 0.HVint: A Strategy for Identifying Novel Protein-Protein Interactions in Herpes Simplex Virus Type 1The NH2 terminus of the herpes simplex virus type 1 regulatory protein ICP0 contains a promoter-specific transcription activation domain.Herpes simplex virus type 1 ICP27-dependent activation of NF-kappaB.Herpes simplex virus 1 ICP4 forms complexes with TFIID and mediator in virus-infected cellsKaposi's sarcoma-associated herpesvirus open reading frame 57 encodes a posttranscriptional regulator with multiple distinct activities.A single amino acid substitution in the ICP27 protein of herpes simplex virus type 1 is responsible for its resistance to leptomycin B.Herpes simplex virus type 1 blocks the apoptotic host cell defense mechanisms that target Bcl-2 and manipulates activation of p38 mitogen-activated protein kinase to improve viral replicationIdentification of a motif in the C terminus of herpes simplex virus regulatory protein ICP4 that contributes to activation of transcriptionThe Epstein-Barr virus SM protein is functionally similar to ICP27 from herpes simplex virus in viral infectionsTransactivation of a viral target gene by herpes simplex virus ICP27 is posttranscriptional and does not require the endogenous promoter or polyadenylation site.Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins.
P2860
Q24537648-4FD39567-37C9-4FC1-AD0C-DC7578A83C3EQ24657245-0FEB1A35-0586-48CD-8803-2691D9411363Q28118543-B5768B2E-F23D-4E63-9E77-B704B3A797B1Q31036498-D0671F3D-70D2-4AE6-AB8B-42CAA4EA4038Q33643356-E6B2EC52-C518-4B9C-8B0A-49F8F4F4B35DQ33644930-C4561D88-1BE7-4A88-B0F5-6E634F969392Q33707490-F61B339F-AE3E-442B-9BD1-4AD18513864EQ33800212-E2DD717B-21D2-4386-B298-4ADDA4DF0B54Q33809422-AF330F19-CB84-460D-8743-46BEF8D02249Q33809951-BA0E1B25-A6A6-4948-937A-DAC457C7CE8DQ33815308-26859C1C-F4FF-490D-B16C-23CDCEF7562BQ33843399-300C8650-1F5F-47B5-AF6E-23FD79935FADQ34178155-83459412-A68A-4563-B982-9FB219081F2BQ34301682-6235D525-F875-4BF4-A4B3-8AC77F5DAF94Q34346572-632B5889-D64D-429D-8695-FFEFF0350E04Q34545620-7BCD8F94-8F42-46FB-8A99-DF1857228BD0Q34552631-A286FAE4-482B-411D-B3CD-44A2F565894AQ34976574-75F0826D-AD7B-4A11-8F8D-FA588F848E5EQ35667107-0EB87F74-5556-43B0-BE6E-9D80C21A8FB6Q35898699-ECF10180-412B-4BEC-BE89-5130A2674AD0Q35949488-C7223C66-3FAD-411E-B2C0-4D8A833FA723Q36214287-4C64B5AA-DB42-49C9-AF93-89F1EBD4DFCCQ36315189-939AB365-0720-4131-AFDC-F98058498B32Q36694202-E3A49772-EA3B-4B5A-A20D-53DF081C2EB2Q37016389-3CB8CB46-ACE2-4DB3-97E9-6018D04FC514Q37059920-4BD20A5A-AFAD-4294-95AB-A6790C778DBBQ37236340-53DD0BCD-D0F6-4644-BAD1-17858B0DA019Q38333502-E94AEF1B-E86C-40EF-BBB5-3D8C45697AD6Q39290324-94146B3D-FE88-40A8-8D9D-E7367E23AA78Q39568162-FB619E9E-10A9-4EA0-8307-CE03BFFD5D4FQ39590466-D28D9EE7-EC71-479B-964C-3450C8A4D19AQ39601658-43A9FCD5-663E-4540-9A29-D6815EFDA5BDQ39610177-6F682857-4D8C-483A-ABE0-8149DEC3FC57Q39681678-9A0D2BA4-FB15-41C8-820C-BD6AD1F798A2Q39684683-A7DA9F4E-FF03-4447-B318-4FABF18FA0F6Q39996395-D217A06C-5FF2-451B-935F-8E23D595D139Q40015345-68122156-F8D2-4CEB-9D9C-63EFA2651FB2
P2860
Physical and functional interactions between herpes simplex virus immediate-early proteins ICP4 and ICP27.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Physical and functional intera ...... early proteins ICP4 and ICP27.
@en
Physical and functional intera ...... early proteins ICP4 and ICP27.
@nl
type
label
Physical and functional intera ...... early proteins ICP4 and ICP27.
@en
Physical and functional intera ...... early proteins ICP4 and ICP27.
@nl
prefLabel
Physical and functional intera ...... early proteins ICP4 and ICP27.
@en
Physical and functional intera ...... early proteins ICP4 and ICP27.
@nl
P2093
P2860
P1433
P1476
Physical and functional intera ...... -early proteins ICP4 and ICP27
@en
P2093
C A Panagiotidis
S J Silverstein
P2860
P304
P407
P577
1997-02-01T00:00:00Z