Canine hemophilia B resulting from a point mutation with unusual consequences
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Animal models of hemophiliaCurrent animal models of hemophilia: the state of the artMan's best friend becomes biology's best in show: genome analyses in the domestic dogLessons Learned from Animal Models of Inherited Bleeding Disorders.The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion.Translational data from adeno-associated virus-mediated gene therapy of hemophilia B in dogsPhenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogsGene therapy for the hemophilias.Gene therapy for hemophilia.Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.Gene therapy: a 2001 perspective.Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.Gene therapy for haemophilia: the end of a 'royal pathology' in the third millennium?Mutation discovery for Mendelian traits in non-laboratory animals: a review of achievements up to 2012.Portal vein delivery of viral vectors for gene therapy for hemophilia.Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins.Protein replacement therapy and gene transfer in canine models of hemophilia A, hemophilia B, von willebrand disease, and factor VII deficiency.Prevention of spontaneous bleeding in dogs with haemophilia A and haemophilia B.In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs.AAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice.Theodore E. Woodward Award. AAV-mediated gene transfer for hemophilia.Novel reporter systems for facile evaluation of I-SceI-mediated genome editingNew findings on animal diseases published since 2003. 1. Dogs.The incidence and distribution of CpG----TpG transitions in the coagulation factor IX gene. A fresh look at CpG mutational hotspotsRegional intravascular delivery of AAV-2-F.IX to skeletal muscle achieves long-term correction of hemophilia B in a large animal modelUnderstanding hereditary diseases using the dog and human as companion model systems.Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B.Large animal models and gene therapy.Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test - Demonstrated in vitro and ex vivo.Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.The efficacy and the risk of immunogenicity of FIX Padua (R338L) in hemophilia B dogs treated by AAV muscle gene therapy.In vivo models of haemophilia - status on current knowledge of clinical phenotypes and therapeutic interventions.Animal models of hemophilia and related bleeding disorders.A web resource on DNA tests for canine and feline hereditary diseases.The Jeremiah Metzger Lecture: gene therapy for inherited disorders: from Christmas disease to Leber's amaurosis.Severe Hemophilia A in a Male Old English Sheep Dog with a C→T Transition that Created a Premature Stop Codon in Factor VIII.Transmission and expansion of HOXB4-induced leukemia in two immunosuppressed dogs: implications for a new canine leukemia modelGene therapy for haemophilia: a long and winding road.Canine models of inherited bleeding disorders in the development of coagulation assays, novel protein replacement and gene therapies.
P2860
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P2860
Canine hemophilia B resulting from a point mutation with unusual consequences
description
1989 nî lūn-bûn
@nan
1989 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Canine hemophilia B resulting from a point mutation with unusual consequences
@ast
Canine hemophilia B resulting from a point mutation with unusual consequences
@en
Canine hemophilia B resulting from a point mutation with unusual consequences
@nl
type
label
Canine hemophilia B resulting from a point mutation with unusual consequences
@ast
Canine hemophilia B resulting from a point mutation with unusual consequences
@en
Canine hemophilia B resulting from a point mutation with unusual consequences
@nl
prefLabel
Canine hemophilia B resulting from a point mutation with unusual consequences
@ast
Canine hemophilia B resulting from a point mutation with unusual consequences
@en
Canine hemophilia B resulting from a point mutation with unusual consequences
@nl
P2093
P2860
P356
P1476
Canine hemophilia B resulting from a point mutation with unusual consequences
@en
P2093
G D Brayer
H M Reisner
K M Brinkhous
P2860
P304
10095-10099
P356
10.1073/PNAS.86.24.10095
P407
P577
1989-12-01T00:00:00Z