Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth. - Wikidata - awgldk - TriplyDB

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.

http://www.wikidata.org/entity/Q34334258

about

Insights into Orphan Nuclear Receptors as Prognostic Markers and Novel Therapeutic Targets for Breast Cancer Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma Research resource: nuclear receptors as transcriptome: discriminant and prognostic value in breast cancer A novel bisindole-PBD conjugate causes DNA damage induced apoptosis via inhibition of DNA repair pathway.Nuclear receptors and pathogenesis of pancreatic cancer.Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells.Induction of Nur77-dependent apoptotic pathway by a coumarin derivative through activation of JNK and p38 MAPK The interplay of NR4A receptors and the oncogene-tumor suppressor networks in cancer Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease.Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors NR4A1 promotes PDGF-BB-induced cell colony formation in soft agar The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells.Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77 Nur77 deficiency leads to systemic inflammation in elderly mice.Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53.Regulation of Nuclear Receptor Nur77 by miR-124.The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3'-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells.Nur77 deficiency in mice accelerates tumor invasion and metastasis by facilitating TNFα secretion and lowering CSF-1R expression.NR4A1 Antagonists Inhibit β1-Integrin-Dependent Breast Cancer Cell Migration.Discovery of 3,3'-diindolylmethanes as potent antileishmanial agents.Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS).1,1-Bis (3'-indolyl)-1-(p-substitutedphenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model.Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes.Minireview: role of orphan nuclear receptors in cancer and potential as drug targets High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome.Nur77 attenuates endothelin-1 expression via downregulation of NF-κB and p38 MAPK in A549 cells and in an ARDS rat model.Orphan nuclear receptor Nurr1 as a potential novel marker for progression in human pancreatic ductal adenocarcinoma.Targeting NR4A1 (TR3) in cancer cells and tumors Nur77: a potential therapeutic target in cancer.Sp1 and the 'hallmarks of cancer'.A comprehensive analysis of candidate genes and pathways in pancreatic cancer.PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1.Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors.Injectable nanofibrous spongy microspheres for NR4A1 plasmid DNA transfection to reverse fibrotic degeneration and support disc regeneration.Nuclear receptor 4A (NR4A) family - orphans no more.The NR4A subfamily of nuclear receptors: potential new therapeutic targets for the treatment of inflammatory diseases.WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.

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P2860

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.

http://www.wikidata.org/entity/Q34334258

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Inactivation of the orphan nuc ...... cancer cell and tumor growth.

@ast

Inactivation of the orphan nuc ...... cancer cell and tumor growth.

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Inactivation of the orphan nuc ...... cancer cell and tumor growth.

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type

label

Inactivation of the orphan nuc ...... cancer cell and tumor growth.

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Inactivation of the orphan nuc ...... cancer cell and tumor growth.

@en

Inactivation of the orphan nuc ...... cancer cell and tumor growth.

@nl

prefLabel

Inactivation of the orphan nuc ...... cancer cell and tumor growth.

@ast

Inactivation of the orphan nuc ...... cancer cell and tumor growth.

@en

Inactivation of the orphan nuc ...... cancer cell and tumor growth.

@nl

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0008-5472.CAN-10-1992

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Cancer Research

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Inactivation of the orphan nuc ...... cancer cell and tumor growth.

@en

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Huamin Wang

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Kyounghyun Kim

http://www.w3.org/2001/XMLSchema#string

Kyungsil Yoon

http://www.w3.org/2001/XMLSchema#string

Maen Abdelrahim

http://www.w3.org/2001/XMLSchema#string

Sabitha Papineni

http://www.w3.org/2001/XMLSchema#string

Stephen Safe

http://www.w3.org/2001/XMLSchema#string

Sudhakar Chintharlapalli

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Syng-Ook Lee

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P2860

A short Nur77-derived peptide converts Bcl-2 from a protector to a killer

Survivin expression and its clinical significance in pancreatic cancer.

Combinatorial control of gene expression by nuclear receptors and coregulators

Nuclear and cytoplasmic survivin: molecular mechanism, prognostic, and therapeutic potential

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

Survivin as a target for new anticancer interventions

Nur77 as a survival factor in tumor necrosis factor signaling

Survivin expression in pancreatic intraepithelial neoplasia (PanIN): steady increase along the developmental stages of pancreatic ductal adenocarcinoma.

Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation.

Molecular mechanism of inhibition of survivin transcription by the GC-rich sequence-selective DNA binding antitumor agent, hedamycin: evidence of survivin down-regulation associated with drug sensitivity

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6824-6836

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scholarly article

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10.1158/0008-5472.CAN-10-1992

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17

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70

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2010-07-21T00:00:00Z

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20660371

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2988472

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