A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
about
NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signalingProtein oligomerization mediated by the transmembrane carboxyl terminal domain of Bcl-XLTargeting Cell Survival Proteins for Cancer Cell DeathTargeting the Bcl-2 family for cancer therapyNovel polymeric nanoparticles for intracellular delivery of peptide Cargos: antitumor efficacy of the BCL-2 conversion peptide NuBCP-9The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptorUpregulation of Bcl2 inhibits apoptosis-driven BAX insertion but favors BAX relocalization in mitochondriaNuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell AdenocarcinomaDeath on the slopes. Symposium on Cell Death Pathways.The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption.Interaction of insulin-like growth factor-binding protein-3 and BAX in mitochondria promotes male germ cell apoptosis.The aryl hydrocarbon receptor is required for induction of p21cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells.The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells.Oligomerization of membrane-bound Bcl-2 is involved in its pore formation induced by tBid.NGFI-B targets mitochondria and induces cardiomyocyte apoptosis in restraint-stressed rats by mediating energy metabolism disorderALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.Human-protein-derived peptides for intracellular delivery of biomolecules.T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunityInactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells.Induction of Nur77-dependent apoptotic pathway by a coumarin derivative through activation of JNK and p38 MAPKReconstitution of the anti-apoptotic Bcl-2 protein into lipid membranes and biophysical evidence for its detergent-driven association with the pro-apoptotic Bax proteinReduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice.Mitochondrial proteomic approach reveals galectin-7 as a novel BCL-2 binding protein in human cells.Quantitative expression analysis and prognostic significance of the BCL2-associated X gene in nasopharyngeal carcinoma: a retrospective cohort study.Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis.Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumorsMitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis.NR4A1 promotes PDGF-BB-induced cell colony formation in soft agarThe orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells.Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule.Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53.The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.Smart self-assembled hybrid hydrogel biomaterialsBax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells.Modes of Cell Death Induced by Photodynamic Therapy Using Zinc Phthalocyanine in Lung Cancer Cells Grown as a Monolayer and Three-Dimensional Multicellular Spheroids.Targeting truncated RXRα for cancer therapy.Targeting truncated retinoid X receptor-α by CF31 induces TNF-α-dependent apoptosis.
P2860
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P2860
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@ast
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@en
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@en-gb
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@nl
type
label
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@ast
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@en
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@en-gb
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@nl
prefLabel
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@ast
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@en
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@en-gb
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@nl
P2093
P2860
P921
P1433
P1476
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
@en
P2093
Arnold C Satterthwait
Bingzhen Lin
Dayong Zhai
Edmond O'Donnell
James Town
Jialing Lin
John C Reed
Shinichi Kitada
P2860
P304
P356
10.1016/J.CCR.2008.09.002
P407
P577
2008-10-01T00:00:00Z