The Bordetella bronchiseptica type III secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearance.
about
Modeling systems-level regulation of host immune responses.Boolean network simulations for life scientists.Inefficient Toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunityO antigen allows B. parapertussis to evade B. pertussis vaccine-induced immunity by blocking binding and functions of cross-reactive antibodies.Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopNImmune regulation of a chronic bacteria infection and consequences for pathogen transmission.Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth.A Type VI secretion system encoding locus is required for Bordetella bronchiseptica immunomodulation and persistence in vivo.Interleukin-1 receptor signaling is required to overcome the effects of pertussis toxin and for efficient infection- or vaccination-induced immunity against Bordetella pertussis.Resident microbiota affect Bordetella pertussis infectious dose and host specificity.Phenotypic modulation of the virulent Bvg phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine.Use of a genetically defined double mutant strain of Bordetella bronchiseptica lacking adenylate cyclase and type III secretion as a live vaccineTranscriptional profiling of Bordetella pertussis reveals requirement of RNA chaperone Hfq for Type III secretion system functionality.Generating super-shedders: co-infection increases bacterial load and egg production of a gastrointestinal helminth.Variation in host susceptibility and infectiousness generated by co-infection: the myxoma-Trichostrongylus retortaeformis case in wild rabbits.Decreased leukocyte accumulation and delayed Bordetella pertussis clearance in IL-6-/- miceSingle-dose, virus-vectored vaccine protection against Yersinia pestis challenge: CD4+ cells are required at the time of challenge for optimal protection.Active and passive immunizations with Bordetella colonization factor A protect mice against respiratory challenge with Bordetella bronchisepticaRole of the type III secretion system in a hypervirulent lineage of Bordetella bronchiseptica.Virulence factor secretion and translocation by Bordetella species.The Bordetella type III secretion system effector BteA contains a conserved N-terminal motif that guides bacterial virulence factors to lipid rafts.IL-10 induction by Bordetella parapertussis limits a protective IFN-gamma response.Toll-like receptor 4 limits transmission of Bordetella bronchiseptica.Vesicular Stomatitis Virus-Vectored Multi-Antigen Tuberculosis Vaccine Limits Bacterial Proliferation in Mice following a Single Intranasal DoseThe Bordetella bronchiseptica type III secretion system is required for persistence and disease severity but not transmission in swine.Development and characterization of attenuated metabolic mutants of Bordetella bronchiseptica for applications in vaccinology.Constraint-based network model of pathogen-immune system interactions.Gamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infection.Snapshot of spatio-temporal cytokine responses to single and co-infections with helminths and bacteria.The O antigen is a critical antigen for the development of a protective immune response to Bordetella parapertussisLack of cross-protection against Bordetella holmesii after pertussis vaccination.Seasonal breeding drives the incidence of a chronic bacterial infection in a free-living herbivore population.Colonization Limits Efficacy, but Not Immunogenicity, of Live-Attenuated Influenza Virus Vaccine and Enhances Pathogenesis After Influenza ChallengeBlood or Serum Exposure Induce Global Transcriptional Changes, Altered Antigenic Profile, and Increased Cytotoxicity by Classical BordetellaeRespiratory Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice
P2860
Q33287189-9C069525-8C14-4175-894D-176DE6DCF73DQ33384933-552B9FA0-F6AE-4090-A17F-AB934E3E1B11Q33402920-302A4A7F-F04E-4BD3-8032-60AA0880CC35Q33502706-601189C7-B9B3-4DB3-A7B0-5EFF84E28F2BQ33590435-DDB4A62B-FD71-4AEC-8E44-D30740FFF3E2Q33672341-E1D248FB-C928-47D6-A6A2-B71A8EC0FEB0Q34130164-44FDAA32-DCAF-4998-B01E-4EA0F8F8E733Q34446897-12D77DB2-4E27-473D-BD50-ABE1BFFF75C8Q34484529-DEBFFF55-8521-4D54-A981-3EF502B3B6BBQ35042275-CE4F667C-8F2C-408C-8776-F153AE92E4A8Q35805470-75C5CB56-FF61-4365-A40D-95821F7A4B28Q35913617-28B31000-99CA-4B15-9165-AECA6E816BF6Q36191639-5EE2CD4B-07ED-4027-B011-58A0C48C2E5FQ36591125-C8B498B9-07DF-4FF5-A135-A81B9337FB3EQ36662611-3E355EF1-F479-40C0-9DBC-ED8857DB6887Q36746359-7C870478-3AB9-46D5-B08A-F2DDB38AC129Q37066697-944E3356-1C40-45B1-BA82-5D09E7A40226Q37075478-A1C3D6EF-3A1F-40CD-B09F-0F7234EC7762Q37333410-0E7D4B20-2EA7-4CCC-810D-F43AF490D6D3Q37382931-F0DD4CB1-C080-4337-AA5D-425A0CEACF98Q37457083-35B23A44-5859-4AB5-AE18-EB16634C7650Q37529638-F7D9F81C-5B15-408A-9F88-8A4F93FE58B7Q37534202-99F0A2DB-6F16-4FC6-B1E7-8A3F51903F6BQ37627029-7D073551-DC06-4AF7-9819-7FB963AE3601Q37643836-94CE46B4-A96D-4E94-BBB9-9E8059F6A8E5Q39335351-F147C7DC-36E6-4AA5-AFA7-1B98CA6B1090Q40033232-5D889291-D503-4C72-889D-798AF7D3FAF0Q41453869-6B898EBE-A79A-42D9-B2DB-8D1F0AC12DEEQ42080014-68A8A954-1467-4EB2-A9D0-D585E2EFF042Q42613134-DAA63D62-04A7-446F-ADA4-134EEAD44E93Q43078103-ECDB0BE4-085C-4C0E-AF3C-46A5EFD19B4CQ51153411-DB619768-5B41-4B96-9B10-CDC587C1E1CFQ58583885-BE547682-B1D2-4C79-8608-A4558C222F8CQ58758919-6C366434-13BA-45A8-B930-BAB52AB2C75EQ58773207-884F3EB8-F1DF-4481-8E48-EB463F16809C
P2860
The Bordetella bronchiseptica type III secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearance.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@ast
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@en
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@nl
type
label
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@ast
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@en
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@nl
prefLabel
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@ast
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@en
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@nl
P2860
P1476
The Bordetella bronchiseptica ...... -mediated bacterial clearance.
@en
P2093
Eric T Harvill
Mylisa R Pilione
P2860
P304
P356
10.1128/IAI.74.2.1043-1049.2006
P407
P577
2006-02-01T00:00:00Z