Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L).
about
A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidizationThe MST/Hippo Pathway and Cell Death: A Non-Canonical AffairhNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencingGenome-wide impact of a recently expanded microRNA cluster in mouseLATS2 is de-methylated and overexpressed in nasopharyngeal carcinoma and predicts poor prognosis.microRNA-605 promotes cell proliferation, migration and invasion in non-small cell lung cancer by directly targeting LATS2.Stability of the LATS2 tumor suppressor gene is regulated by tristetraprolinThe RASSF1A tumor suppressor activates Bax via MOAP-1.MicroRNA as a Novel Modulator in Head and Neck Squamous CarcinomaDynamics of DNA damage induced pathways to cancerDeath pathways triggered by activated Ras in cancer cellsAberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.Upregulation of miR-372 and -373 associates with lymph node metastasis and poor prognosis of oral carcinomas.Lower Levels of Human MOB3B Are Associated with Prostate Cancer Susceptibility and Aggressive Clinicopathological Characteristics.Hypermethylation of the large tumor suppressor genes in Japanese lung cancer.KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis.Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas.A genetic variant in large tumor suppressor kinase 2 of Hippo signaling pathway contributes to prognosis of hepatocellular carcinoma.Cancer testis antigens: novel biomarkers and targetable proteins for ovarian cancer.RASSF Signalling and DNA Damage: Monitoring the Integrity of the Genome?Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis.Copper alters the conformation and transcriptional activity of the tumor suppressor protein p53 in human Hep G2 cells.Roles of the Hippo pathway in lung development and tumorigenesis.The clinical significance and biological function of large tumour suppressor 2 in hepatocellular carcinoma.LATS2 induced by TNF-alpha and inhibited cell proliferation and invasion by phosphorylating YAP in oral squamous cell carcinoma.Down-regulation of LATS2 in non-small cell lung cancer promoted the growth and motility of cancer cells.Hippo pathway deregulation: implications in the pathogenesis of haematological malignancies.Phosphorylation target site specificity for AGC kinases DMPK E and Lats2.The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway.Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis through activation of Stat3/Bcl-XL pathway.RNAi-based functional selection identifies novel cell migration determinants dependent on PI3K and AKT pathways.Intersecting transcriptomic profiling technologies and long non-coding RNA function in lung adenocarcinoma: discovery, mechanisms, and therapeutic applications.Downregulation of MiR-31 stimulates expression of LATS2 via the hippo pathway and promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma.miR-372 promotes breast cancer cell proliferation by directly targeting LATS2.[Role of Hippo Signaling Pathway in Lung Cancer].Molecular Alterations and Expression Dynamics of LATS1 and LATS2 Genes in Non-Small-Cell Lung Carcinoma.The expression of COX-2, hTERT, MDM2, LATS2 and S100A2 in different types of non-small cell lung cancer (NSCLC).Lats2 is an essential mitotic regulator required for the coordination of cell division.The expression analysis of LATS2 gene in de novo AML patients.
P2860
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P2860
Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L).
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Putative tumor suppressor Lats ...... nregulation of Bcl-2 and Bcl-x
@nl
Putative tumor suppressor Lats ...... ulation of Bcl-2 and Bcl-x(L).
@ast
Putative tumor suppressor Lats ...... ulation of Bcl-2 and Bcl-x(L).
@en
type
label
Putative tumor suppressor Lats ...... nregulation of Bcl-2 and Bcl-x
@nl
Putative tumor suppressor Lats ...... ulation of Bcl-2 and Bcl-x(L).
@ast
Putative tumor suppressor Lats ...... ulation of Bcl-2 and Bcl-x(L).
@en
prefLabel
Putative tumor suppressor Lats ...... nregulation of Bcl-2 and Bcl-x
@nl
Putative tumor suppressor Lats ...... ulation of Bcl-2 and Bcl-x(L).
@ast
Putative tumor suppressor Lats ...... ulation of Bcl-2 and Bcl-x(L).
@en
P2093
P1476
Putative tumor suppressor Lats ...... ulation of Bcl-2 and Bcl-x(L).
@en
P2093
Ameeta Kelekar
Hengning Ke
Tishonna Woods
P304
P356
10.1016/J.YEXCR.2004.04.031
P407
P577
2004-08-01T00:00:00Z