Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines. - Wikidata - awgldk - TriplyDB

Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines.

Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines.

http://www.wikidata.org/entity/Q34335798

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Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression Microbiota impact on the epigenetic regulation of colorectal cancer The RUNX genes: gain or loss of function in cancer STAT3 signaling contributes to the high effector activities of interleukin-15-derived dendritic cells RUNX3 has an oncogenic role in head and neck cancer Identification of a new pebp2alphaA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro.Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues.RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.Association between RUNX3 promoter methylation and gastric cancer: a meta-analysis RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD.Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis RUNX3 mediates suppression of tumor growth and metastasis of human CCRCC by regulating cyclin related proteins and TIMP-1.Genome-wide screening of genes regulated by DNA methylation in colon cancer development.Epigenetic regulation of lymphoid specific gene sets.Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation.The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome.Methylation profiles of CpG island loci in major types of human cancers Downregulation of the RUNX3 gene by promoter hypermethylation and hemizygous deletion in breast cancer.Biology of SNU cell lines.Oncogenic role of RUNX3 in head and neck cancer.Loss of runt-related transcription factor 3 causes development and progression of hepatocellular carcinoma.Clinical significance and association of RUNX3 hypermethylation frequency with colorectal cancer: a meta-analysis The Role of Stem Cell DNA Methylation in Colorectal Carcinogenesis.Loss of RUNX3 expression may contribute to poor prognosis in patients with chondrosarcoma.RUNX3 downregulation in human lung adenocarcinoma is independent of p53, EGFR or KRAS status.Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma.UnPAKing RUNX3 functions-Both sides of the coin.Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3.RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration.Expression of RUNX3 in skin cancers.Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines.Alteration in the expression of MGMT and RUNX3 due to non-CpG promoter methylation and their correlation with different risk factors in esophageal cancer patients.Dynamic DNA methylation and histone modifications contribute to lentiviral transgene silencing in murine embryonic carcinoma cells RUNX3 Promoter Methylation Is Associated with Hepatocellular Carcinoma Risk: A Meta-Analysis.Investigation of methylation and protein expression of the Runx3 gene in colon carcinogenesis.RUNX3 protein is overexpressed in human basal cell carcinomas.RUNX3 inactivation in colorectal polyps arising through different pathways of colonic carcinogenesis.Truncated forms of RUNX3 Unlike Full Length Protein Alter Cell Proliferation in a TGF-β Context Dependent Manner.

P2860

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P2860

Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines.

http://www.wikidata.org/entity/Q34335798

description

2004 nî lūn-bûn

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2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Promoter hypermethylation down ...... colorectal cancer cell lines.

@ast

Promoter hypermethylation down ...... colorectal cancer cell lines.

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Promoter hypermethylation down ...... colorectal cancer cell lines.

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type

label

Promoter hypermethylation down ...... colorectal cancer cell lines.

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Promoter hypermethylation down ...... colorectal cancer cell lines.

@en

Promoter hypermethylation down ...... colorectal cancer cell lines.

@nl

prefLabel

Promoter hypermethylation down ...... colorectal cancer cell lines.

@ast

Promoter hypermethylation down ...... colorectal cancer cell lines.

@en

Promoter hypermethylation down ...... colorectal cancer cell lines.

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Promoter hypermethylation down ...... colorectal cancer cell lines.

@en

P2093

Hio Chung Kang

http://www.w3.org/2001/XMLSchema#string

Il-Jin Kim

http://www.w3.org/2001/XMLSchema#string

Inn-Oc Han

http://www.w3.org/2001/XMLSchema#string

Ja-Lok Ku

http://www.w3.org/2001/XMLSchema#string

Jae-Gahb Park

http://www.w3.org/2001/XMLSchema#string

Joo-Ho Shin

http://www.w3.org/2001/XMLSchema#string

Sung-Bum Kang

http://www.w3.org/2001/XMLSchema#string

Sung-Hye Hong

http://www.w3.org/2001/XMLSchema#string

Young-Kyoung Shin

http://www.w3.org/2001/XMLSchema#string

P2860

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

Causal relationship between the loss of RUNX3 expression and gastric cancer

The RUNX3 gene--sequence, structure and regulated expression.

DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines.

Expression pattern, regulation, and biological role of runt domain transcription factor, run, in Caenorhabditis elegans

RUNX transcription factors as key targets of TGF-beta superfamily signaling.

5'-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer.

Establishment and characterisation of six human biliary tract cancer cell lines.

Prognostic value of chromosome 1p allelic loss in colon cancer.

Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma.

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6736-6742

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10.1038/SJ.ONC.1207731

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40

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23

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1040265980

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15273736

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colorectal cancer