Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin.
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PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1Anticancer agent shikonin is an incompetent inducer of cancer drug resistanceTRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC.Molecular determinants of caste differentiation in the highly eusocial honeybee Apis melliferaShikonin inhibits the growth of human prostate cancer cells via modulation of the androgen receptor.An improved transplantation strategy for mouse mesenchymal stem cells in an acute myocardial infarction model.Prostate cancer regulatory networksThe mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicityOverexpression of tumor necrosis factor receptor-associated protein 1 (TRAP1), leads to mitochondrial aberrations in mouse fibroblast NIH/3T3 cells.Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2.Utilization of the cellular stress response to sensitize cancer cells to TRAIL-mediated apoptosis.TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expressionGlobal gene expression and Ingenuity biological functions analysis on PCBs 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities.Delayed phosphorylation of classical protein kinase C (PKC) substrates requires PKC internalization and formation of the pericentrion in a phospholipase D (PLD)-dependent mannerTNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive FormThe Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology.Broad targeting of resistance to apoptosis in cancer.Quantitative proteomics analysis of the effects of ionizing radiation in wild type and p53 K317R knock-in mouse thymocytesAberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer.Past, present, and emerging roles of mitochondrial heat shock protein TRAP1 in the metabolism and regulation of cancer stem cells.Hsp90 regulation of mitochondrial protein folding: from organelle integrity to cellular homeostasisMitochondrial protein targets of thiol-reactive electrophilesMitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalanceCompartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones.DNA Microarray-Based Screening and Characterization of Traditional Chinese Medicine.Cadmium as a transcriptional modulator in human cells.TRAP-1, the mitochondrial Hsp90.Shikonin and its derivatives: a patent review.The mitochondrial permeability transition pore and its adaptive responses in tumor cells.Organelle-specific Hsp90 inhibitors.Shikonin Inhibits the Proliferation of Human Breast Cancer Cells by Reducing Tumor-Derived Exosomes.Overexpression of tumor necrosis factor receptor-associated protein 1 (TRAP1) are associated with poor prognosis of epithelial ovarian cancer.Suppression of tumor necrosis factor receptor-associated protein 1 expression induces inhibition of cell proliferation and tumor growth in human esophageal cancer cells.The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells.TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins.Impairment of oxidative stress-induced heme oxygenase-1 expression by the defect of Parkinson-related gene of PINK1.Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis.Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients.Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease.
P2860
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P2860
Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Involvement of tumor necrosis ...... eta-hydroxyisovalerylshikonin.
@ast
Involvement of tumor necrosis ...... eta-hydroxyisovalerylshikonin.
@en
Involvement of tumor necrosis factor receptor-associated protein 1
@nl
type
label
Involvement of tumor necrosis ...... eta-hydroxyisovalerylshikonin.
@ast
Involvement of tumor necrosis ...... eta-hydroxyisovalerylshikonin.
@en
Involvement of tumor necrosis factor receptor-associated protein 1
@nl
prefLabel
Involvement of tumor necrosis ...... eta-hydroxyisovalerylshikonin.
@ast
Involvement of tumor necrosis ...... eta-hydroxyisovalerylshikonin.
@en
Involvement of tumor necrosis factor receptor-associated protein 1
@nl
P2093
P2860
P356
P1476
Involvement of tumor necrosis ...... eta-hydroxyisovalerylshikonin.
@en
P2093
Genryu Shima
Kazuyasu Nakaya
Kouichi Hori
Masayo Horie
Sachiko Kajimoto
Shigeo Nakajo
Toshihiro Aiuchi
Toshiko Shibayama-Imazu
Yutaka Masuda
P2860
P304
42503-42515
P356
10.1074/JBC.M404256200
P407
P577
2004-07-28T00:00:00Z