Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia. - Wikidata - awgldk - TriplyDB

Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.

Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.

http://www.wikidata.org/entity/Q34338550

about

Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts Mammalian Krüppel-like factors in health and diseases Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration Virus-free induction of pluripotency and subsequent excision of reprogramming factors The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology Cancer Stem Cell Hierarchy in Glioblastoma Multiforme Endothelial Transdifferentiation of Tumor Cells Triggered by the Twist1-Jagged1-KLF4 Axis: Relationship between Cancer Stemness and Angiogenesis Defining the Communication between Agonist and Coactivator Binding in the Retinoid X Receptor Ligand Binding Domain Induced pluripotent stem cell potential in medicine, specifically focused on reproductive medicine Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis Transcriptomic Analysis Shows Decreased Cortical Expression of NR4A1, NR4A2 and RXRB in Schizophrenia and Provides Evidence for Nuclear Receptor Dysregulation Gut-enriched Krüppel-like factor interaction with Smad3 inhibits myofibroblast differentiation Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.Cooperative transcriptional activation by Klf4, Meis2, and Pbx1 Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.Expression of Krüppel-like factor 4 in breast cancer tissues and its effects on the proliferation of breast cancer MDA-MB-231 cells.KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial-Mesenchymal Transition.KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth.Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytes.Advances in reprogramming somatic cells to induced pluripotent stem cells.Klf4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice.Chemical biology in stem cell research.Local microenvironment provides important cues for cell differentiation in lingual epithelia.Krüppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression.Keratinocyte-targeted expression of human laminin γ2 rescues skin blistering and early lethality of laminin γ2 deficient mice.The transcription factor KLF4 as an independent predictive marker for pathologic complete remission in breast cancer neoadjuvant chemotherapy: a case-control study Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition.KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia.Stem cells in clinical practice: applications and warnings.MicroRNAs 206 and 21 cooperate to promote RAS-extracellular signal-regulated kinase signaling by suppressing the translation of RASA1 and SPRED1 Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8).Regulation of Krüppel-like factor 4 by the anaphase promoting complex pathway is involved in TGF-beta signaling.Krüppel-like factor 4 is involved in functional differentiation of testicular Sertoli cells.Attenuation of krüppel-like factor 4 facilitates carcinogenesis by inducing g1/s phase arrest in clear cell renal cell carcinoma Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion.Putative tumor-suppressive function of Kruppel-like factor 4 in primary lung carcinoma.Krüppel-like factor 4 (KLF4) activates the transcription of the gene for the platelet isoform of phosphofructokinase (PFKP) in breast cancer.A KLF4-miRNA-206 autoregulatory feedback loop can promote or inhibit protein translation depending upon cell context.Induction of KLF4 in response to heat stress.

P2860

Q21245753-254060B0-02F1-4723-8916-0F323F3EEE4D Q24612560-221DC288-0BDD-4D74-A747-8159A0FFE91A Q24617620-A5228A2C-D3B6-481F-9C4B-C631060163AE Q24644686-EE6B5915-329E-4EA2-BFC7-59F18B839F1D Q24647882-67947BC0-8AA8-418E-89B3-3255DD434D62 Q26752312-3078A5F9-BD20-43FD-A10E-B0E10F2ECC46 Q26773015-9F4597B4-C7DD-4712-94B6-9756813146C7 Q27680515-1C4DF99D-F300-4774-A726-318F38CEF8C1 Q28083057-8DC5A94A-3FF8-41ED-884C-31E4E427CB7B Q28504494-A2FB94FA-251C-4334-B8B8-6505564BC091 Q28555095-91664FC2-3093-4C33-A56B-D9FE141B392D Q28582127-BED398BD-2295-4CFD-96AC-1A9F075E2E11 Q29398901-B83EA451-39D4-4A5D-B03A-E1D212CFDEE9 Q30299921-4646C1FA-C823-45BD-AF8E-193123809F7C Q30428157-492AC548-1831-4A97-AC1D-CC378C942E1F Q30667326-451A4B4E-7CE4-4C31-8A32-0B18001A6719 Q33723841-36D4EC3A-7962-4F7F-BE4F-3A1F8DD0A94F Q33756048-15DDD0E2-23B6-4F86-8F6D-960A85A5D31D Q33809921-DA289517-BA95-4C4B-99FB-7AEE492419EA Q33815952-FEF6FFC4-73F8-48A2-95B3-6189FC63DF02 Q34106626-92E5C00C-DB55-4E8C-A665-C3638615EC54 Q34135989-1E994916-9685-48C4-86A5-3D3B66240D6C Q34174339-C114791D-0162-4699-8855-0D66888F9873 Q34238983-2A219649-95BB-4AB1-88A5-928AEEA14B47 Q34399237-EBC25CA4-2B20-422D-BC0C-6238F78BA046 Q34429347-261E41F7-D34A-4DF8-B7AA-133115A2B187 Q34434819-762A8E96-E300-4D90-ADDD-7CE1DE032BB9 Q34462874-B0CAB6FA-921B-44E0-9EC8-8353A1D43A96 Q34477044-0E7C87CD-D27E-4329-8EC9-71CA7BA3E339 Q34552765-B650081C-AB5C-472B-A819-0B38BFC7476E Q34592684-72D45A69-AAB1-4B32-88EC-A24660C21DFE Q34603384-1EC2A78C-919B-414F-9A86-050D6C4F7A89 Q34606049-C5E374EB-DDB0-44B2-B042-3DE100A88AD5 Q34744650-1CFF475F-5D0D-468D-8112-4CE7B8EE2AFD Q34826101-7F355334-0154-4FD5-962B-4FAA8D8E699A Q34939838-726AC657-314B-4769-8844-16EBDDDA591A Q35001648-C1C16114-62C9-4EAD-8DAE-83EFF79EADDF Q35085017-DC950261-0946-43DC-B63D-7220473DD434 Q35096699-C63885BD-8ABA-4E7F-8459-6323A71270F6 Q35239578-2385F589-6E98-47AE-9703-7F031EEF47F2

P2860

Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.

http://www.wikidata.org/entity/Q34338550

description

2005 nî lūn-bûn

@nan

2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@ast

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@en

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@nl

type

label

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@ast

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@en

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@nl

prefLabel

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@ast

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@en

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@nl

P1433

Q34338550-89BDC4C9-98D4-4529-8F40-7F5E220E23C4

P1476

Q34338550-8DD2F375-041A-4D43-8482-C7940DD9B3E7

P2093

Q34338550-04D56597-95D4-4A7D-A1C2-42EC89F36854

Q34338550-1A0346AA-DAB7-42C6-9B0E-A0765EA1B15E

Q34338550-2BBB19A8-CB44-435F-8F32-CB8FF320FD0B

Q34338550-3B5651FF-B82A-4AA0-9D4C-20E9EEA38874

Q34338550-3C06CD46-1E4F-4D65-B396-17549F908557

Q34338550-54A8219A-E81D-46FA-BC53-C32A4A1F5816

Q34338550-593BC7DA-CFB5-49C7-BF98-E1CEACB07250

Q34338550-853F5F92-F131-4854-A54B-44822DA06168

Q34338550-CFCE8D34-D37B-4731-AF74-5571DD463D70

Q34338550-DF71DC8C-8F8F-4BAF-8A28-52C72A6479E7

P2860

Q34338550-0242A6C3-D32B-4580-BBF1-386C36E2969D

Q34338550-03E371BE-4F7B-4CF2-AAD1-DE61C9457023

Q34338550-03F002BD-AB78-4DE1-8FD4-E7B63DAF3201

Q34338550-05092D45-2697-4D70-AD03-7FB503829ABB

Q34338550-05695D41-739E-48F9-B19C-65F3674313EA

Q34338550-06049149-BC6D-4276-95A4-B919485317BE

Q34338550-0BFF6B42-7F21-4092-804E-68858614D0EE

Q34338550-10416AD3-FCF9-4144-99A0-1BDF4AC7D6BB

Q34338550-17ED1399-D49F-4BBB-90C9-BFA6A4FFB4CB

Q34338550-1B47BAB0-FDB5-496A-ABF2-A750292524DF

P2888

Q34338550-69ED766D-2058-4774-916D-E10DECA44F5A

P304

Q34338550-14DE1FBE-1192-4CAD-A8C2-7E4C262BDC9A

P31

Q34338550-8153294B-F083-4AC2-A7EB-C95CC829DEEA

P356

Q34338550-211487A9-4C7D-46C7-B530-B123920DC629

P407

Q34338550-C19FEC0D-B5C3-4C89-80D3-2FCCAAF9AD51

P433

Q34338550-68749843-814F-4A17-B0C9-07737A94E4B1

P478

Q34338550-2BD91538-7C62-4C25-ABEC-C850EED4299E

P50

Q34338550-D16FF96A-9D32-40AC-AF5D-04108943C94A

P577

Q34338550-37C58A49-67A9-4570-AD21-49AF65DA4E44

P5875

Q34338550-E6323668-FBF5-4F3A-989D-5AC5C52F1EF8

P6179

Q34338550-48BEAE57-4A1A-4F43-B8D8-A1672D2EEB50

P698

Q34338550-7CEE762A-F2E3-425D-A946-E4EE9774F527

P932

Q34338550-20080C66-0445-4873-833D-DCBB65036237

P356

P1433

P1476

Induction of KLF4 in basal ker ...... squamous epithelial dysplasia.

@en

P2093

Andra R Frost

http://www.w3.org/2001/XMLSchema#string

Andrew J Paterson

http://www.w3.org/2001/XMLSchema#string

Clinton D Nail

http://www.w3.org/2001/XMLSchema#string

J Michael Ruppert

http://www.w3.org/2001/XMLSchema#string

Jeffrey E Kudlow

http://www.w3.org/2001/XMLSchema#string

K Wade Foster

http://www.w3.org/2001/XMLSchema#string

Sarah K Bailey

http://www.w3.org/2001/XMLSchema#string

Susan M Lobo-Ruppert

http://www.w3.org/2001/XMLSchema#string

Thomas J Fitzgerald

http://www.w3.org/2001/XMLSchema#string

Tim M Townes

http://www.w3.org/2001/XMLSchema#string

P2860

The Hallmarks of Cancer

Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells

Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity

The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion

The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter

Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Klf4 is a transcription factor required for establishing the barrier function of the skin

P2888

P304

1491-1500

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1208307

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

24

http://www.w3.org/2001/XMLSchema#string

P50

Iuri Drumond Louro

P577

2005-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8058240

http://www.w3.org/2001/XMLSchema#string

P6179

1020853821

http://www.w3.org/2001/XMLSchema#string

P698

15674344

http://www.w3.org/2001/XMLSchema#string

P932

1361530

http://www.w3.org/2001/XMLSchema#string