Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel.
about
G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclaseIsolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunitsBinding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinaseA discrete alcohol pocket involved in GIRK channel activationA recombinant inwardly rectifying potassium channel coupled to GTP-binding proteinsThe selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic systemSlow modal gating of single G protein-activated K+ channels expressed in Xenopus oocytesMuscarinic K+ channel in the heart. Modal regulation by G protein beta gamma subunitsKir3 channel signaling complexes: focus on opioid receptor signalingUnravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approachesThe cellular and molecular basis of bitter tastant-induced bronchodilationCrystal structure of a Kir3.1-prokaryotic Kir channel chimeraMechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and SodiumX-ray structure of the mammalian GIRK2–βγ G-protein complexGialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptorsEvidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.Identification of a Kir3.4 mutation in congenital long QT syndromeGlycosylation of GIRK1 at Asn119 and ROMK1 at Asn117 has different consequences in potassium channel functionFunctional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3Activator of G-protein signaling 1 blocks GIRK channel activation by a G-protein-coupled receptor: apparent disruption of receptor signaling complexesActivation of the calcium-permeable cation channel CD20 by alpha subunits of the Gi proteinNumber and stoichiometry of subunits in the native atrial G-protein-gated K+ channel, IKAChGbeta binding to GIRK4 subunit is critical for G protein-gated K+ channel activationIdentification of native atrial G-protein-regulated inwardly rectifying K+ (GIRK4) channel homomultimersInhibition of an inward rectifier potassium channel (Kir2.3) by G-protein betagamma subunitsMechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channelsKir3.1/3.2 encodes an I(KACh)-like current in gastrointestinal myocytesEffect of G protein heterotrimer composition on coupling of neurotransmitter receptors to N-type Ca(2+) channel modulation in sympathetic neuronsProtein kinase C alters the responsiveness of adenylyl cyclases to G protein alpha and betagamma subunitsEndothelin-induced, long lasting, and Ca2+ influx-independent blockade of intrinsic secretion in pituitary cells by Gz subunitsActivation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein beta gamma subunits.Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger.Role of the prenyl group on the G protein gamma subunit in coupling trimeric G proteins to A1 adenosine receptors.Molecular mechanisms of go signalingMuscarinic receptor functioning and distribution in the eye: molecular basis and implications for clinical diagnosis and therapy.Heterotrimeric G proteins in heart disease.G-protein mediated gating of inward-rectifier K+ channels.Controlling potassium channel activities: Interplay between the membrane and intracellular factors.Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system.
P2860
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P2860
Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@ast
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@en
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@nl
type
label
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@ast
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@en
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@nl
prefLabel
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@ast
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@en
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@nl
P2093
P356
P1433
P1476
Recombinant G-protein beta gam ...... ated atrial potassium channel.
@en
P2093
A G Gilman
D E Clapham
G B Krapivinsky
J A Iñiguez-Lluhl
K D Wickman
M E Linder
P A Davenport
P2888
P304
P356
10.1038/368255A0
P407
P577
1994-03-01T00:00:00Z
P5875
P6179
1021008116