Higher throughput calorimetry: opportunities, approaches and challenges. - Wikidata - awgldk - TriplyDB

Higher throughput calorimetry: opportunities, approaches and challenges.

Higher throughput calorimetry: opportunities, approaches and challenges.

http://www.wikidata.org/entity/Q34338992

about

X-ray crystallography over the past decade for novel drug discovery - where are we heading next?Fragment screening and HIV therapeutics Recent developments in the use of differential scanning fluorometry in protein and small molecule discovery and characterization Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography Towards an Automated MEMS-based Characterization of Benign and Cancerous Breast Tissue using Bioimpedance Measurements.High-precision isothermal titration calorimetry with automated peak-shape analysis.Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions.Applications of isothermal titration calorimetry in pure and applied research--survey of the literature from 2010.High-throughput fragment screening by affinity LC-MS.A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline.High-Throughput Screening by Nuclear Magnetic Resonance (HTS by NMR) for the Identification of PPIs Antagonists Accurate label-free reaction kinetics determination using initial rate heat measurements.Melting thermodynamics of reversible DNA/ligand complexes at interfaces.A Multichannel Calorimetric Simultaneous Assay Platform Using a Microampere Constant-Current Looped Enthalpy Sensor Array.Thermodynamic studies for drug design and screening.Ligand-receptor interaction platforms and their applications for drug discovery.NMR-based approaches for the identification and optimization of inhibitors of protein-protein interactions.Designer protein delivery: From natural to engineered affinity-controlled release systems.The impact of binding thermodynamics on medicinal chemistry optimizations.Interactions of cisplatin analogues with lysozyme: a comparative analysis.Extent of enthalpy-entropy compensation in protein-ligand interactions.Micro-differential scanning calorimeter for liquid biological samples.A comparative study of capillary electrophoresis and isothermal titration calorimetry for the determination of binding constant of human serum albumin to monoclonal antibody.A fast and reliable method for monitoring of prophage-activating chemicals.Magnetically-Actuated Mixing and Merging of Acid-Base Micro-Droplets on Open Surfaces: Preliminary Study.Translating molecular detections into a simple temperature test using a target-responsive smart thermometer.

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Higher throughput calorimetry: opportunities, approaches and challenges.

http://www.wikidata.org/entity/Q34338992

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Higher throughput calorimetry: opportunities, approaches and challenges.

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Higher throughput calorimetry: opportunities, approaches and challenges.

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Higher throughput calorimetry: opportunities, approaches and challenges.

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type

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Higher throughput calorimetry: opportunities, approaches and challenges.

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Higher throughput calorimetry: opportunities, approaches and challenges.

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Higher throughput calorimetry: opportunities, approaches and challenges.

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Higher throughput calorimetry: opportunities, approaches and challenges.

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Higher throughput calorimetry: opportunities, approaches and challenges.

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Higher throughput calorimetry: opportunities, approaches and challenges.

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J.SBI.2010.09.001

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Current Opinion in Structural Biology

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Higher throughput calorimetry: opportunities, approaches and challenges.

@en

P2093

Francisco E Torres

http://www.w3.org/2001/XMLSchema#string

Glyn Williams

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Joseph E Coyle

http://www.w3.org/2001/XMLSchema#string

Michael I Recht

http://www.w3.org/2001/XMLSchema#string

Richard H Bruce

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BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

Entropic contribution to the linking coefficient in fragment based drug design: a case study

Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency

Approaches to the description and prediction of the binding affinity of small-molecule ligands to macromolecular receptors

Fragment-based lead discovery: leads by design

Ligand efficiency: a useful metric for lead selection

Isothermal titration calorimetry: experimental design, data analysis, and probing macromolecule/ligand binding and kinetic interactions.

Identification of novel fragment compounds targeted against the pY pocket of v-Src SH2 by computational and NMR screening and thermodynamic evaluation.

Isothermal titration calorimetry in drug discovery.

Heat capacity and entropy changes in processes involving proteins.

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598-605

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scholarly article

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10.1016/J.SBI.2010.09.001

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5

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20

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47299305

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20888754

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