Novel PINK1 mutations in early-onset parkinsonism. - Wikidata - awgldk - TriplyDB

Novel PINK1 mutations in early-onset parkinsonism.

Novel PINK1 mutations in early-onset parkinsonism.

http://www.wikidata.org/entity/Q34345898

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Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease Transgenic rodent models of Parkinson’s disease Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1 Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.GBA server: EST-based digital gene expression profiling Ubiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatment Ceramide induced mitophagy and tumor suppression Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons.Mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice.Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2 Significance of the parkin and PINK1 gene in Jordanian families with incidences of young-onset and juvenile parkinsonism PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease.Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1.Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells Unveiling clusters of RNA transcript pairs associated with markers of Alzheimer's disease progression.Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases.The genetics of Parkinson disease.Transgenic animal models of neurodegeneration based on human genetic studies.Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing.Unfolded protein stress in the endoplasmic reticulum and mitochondria: a role in neurodegeneration Population genetic approaches to neurological disease: Parkinson's disease as an example.PINK1 mutation heterozygosity and the risk of Parkinson's disease.Co-occurrence of affective and schizophrenia spectrum disorders with PINK1 mutations Differential submitochondrial localization of PINK1 as a molecular switch for mediating distinct mitochondrial signaling pathways.Recessive Parkinson's disease.Biology of mitochondria in neurodegenerative diseases.Parkinson's disease: the genetics of a heterogeneous disorder.Reduced mitochondrial DNA copy number is a biomarker of Parkinson's disease.Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila Congenital disease SNPs target lineage specific structural elements in protein kinases Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration.Genetics of Parkinson disease.Progress in the pathogenesis and genetics of Parkinson's disease.

P2860

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P2860

Novel PINK1 mutations in early-onset parkinsonism.

http://www.wikidata.org/entity/Q34345898

description

2004 nî lūn-bûn

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2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

@zh-hk

2004年論文

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2004年論文

@zh-tw

2004年论文

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name

Novel PINK1 mutations in early-onset parkinsonism.

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Novel PINK1 mutations in early-onset parkinsonism.

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Novel PINK1 mutations in early-onset parkinsonism.

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type

label

Novel PINK1 mutations in early-onset parkinsonism.

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Novel PINK1 mutations in early-onset parkinsonism.

@en

Novel PINK1 mutations in early-onset parkinsonism.

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prefLabel

Novel PINK1 mutations in early-onset parkinsonism.

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Novel PINK1 mutations in early-onset parkinsonism.

@en

Novel PINK1 mutations in early-onset parkinsonism.

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P1433

Annals of Neurology

P1476

Novel PINK1 mutations in early-onset parkinsonism.

@en

P2093

Arlene R Ng

http://www.w3.org/2001/XMLSchema#string

Chin-Song Lu

http://www.w3.org/2001/XMLSchema#string

Hiroyo Yoshino

http://www.w3.org/2001/XMLSchema#string

Hiroyuki Tomiyama

http://www.w3.org/2001/XMLSchema#string

Kenichi Sato

http://www.w3.org/2001/XMLSchema#string

Masato Asahina

http://www.w3.org/2001/XMLSchema#string

Nobuyoshi Shimizu

http://www.w3.org/2001/XMLSchema#string

Raymond L Rosales

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Sharon Hassin-Baer

http://www.w3.org/2001/XMLSchema#string

Shuichi Asakawa

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P2860

DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.

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424-427

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scholarly article

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10.1002/ANA.20251

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3

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56

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Nobutaka Hattori

Yoshikuni Mizuno

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2004-09-01T00:00:00Z

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15349870

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P921

Parkinson's disease