DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.
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Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation updateOxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factorAge-dependent motor deficits and dopaminergic dysfunction in DJ-1 null miceDJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidaseGenetic mouse models of parkinsonism: strengths and limitations.Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.High-throughput homogeneous mass cleave assay technology for the diagnosis of autosomal recessive Parkinson's diseaseGenes associated with Parkinson syndrome.Copy number variability in Parkinson's disease: assembling the puzzle through a systems biology approachDJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity.Parkinson's disease: Exit toxins, enter geneticsPINK1 mutations are associated with sporadic early-onset parkinsonism.Novel PINK1 mutations in early-onset parkinsonism.Human DJ-1-specific transcriptional activation of tyrosine hydroxylase genePathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease.Transgenic animal models of neurodegeneration based on human genetic studies.Mutations in DJ-1 are rare in familial Parkinson diseaseOxidized DJ-1 interacts with the mitochondrial protein BCL-XL.Keap1-Nrf2 activation in the presence and absence of DJ-1.Splicing: is there an alternative contribution to Parkinson's disease?Dysregulation of the causative genes for hereditary parkinsonism in the midbrain in Parkinson's disease.Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?The genetics of Parkinson disease: Implications for neurological care.Mutations in the glucocerebrosidase gene are associated with early-onset Parkinson disease.Update on the genetics of Parkinson's disease.Emerging pathways in genetic Parkinson's disease: autosomal-recessive genes in Parkinson's disease--a common pathway?Complicated recessive dystonia parkinsonism syndromes.DJ1 analysis in a large cohort of Italian early onset Parkinson Disease patients.The E163K DJ-1 mutant shows specific antioxidant deficiency.Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6.Genetic insights into sporadic Parkinson's disease pathogenesis.Rare causes of dystonia parkinsonism.Milestones in PD genetics.Synaptic protein alterations in Parkinson's disease.Systematic review and UK-based study of PARK2 (parkin), PINK1, PARK7 (DJ-1) and LRRK2 in early-onset Parkinson's disease.Animal models of Parkinson's disease: a gateway to therapeutics?Defining the human copper proteome and analysis of its expression variation in cancers.Parkinson's disease: genetics and beyond.
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P2860
DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
DJ-1 (PARK7) mutations are les ...... early-onset Parkinson disease.
@en
DJ-1
@nl
type
label
DJ-1 (PARK7) mutations are les ...... early-onset Parkinson disease.
@en
DJ-1
@nl
prefLabel
DJ-1 (PARK7) mutations are les ...... early-onset Parkinson disease.
@en
DJ-1
@nl
P2093
P1433
P1476
DJ-1 (PARK7) mutations are les ...... early-onset Parkinson disease.
@en
P2093
A Djarmati
C Wellenbrock
E Schwinger
L J Ozelius
P304
P356
10.1212/01.WNL.0000113022.51739.88
P407
P577
2004-02-01T00:00:00Z