Targeting protein-protein interactions as an anticancer strategy
about
Human Prostate Cancer Hallmarks MapUnlocking the secrets to protein-protein interface drug targets using structural mass spectrometry techniquesA versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real timeCharacterization of Promiscuous Binding of Phosphor Ligands to Breast-Cancer-Gene 1 (BRCA1) C-Terminal (BRCT): Molecular Dynamics, Free Energy, Entropy and Inhibitor DesignStructural bioinformatics of the interactome.Targeting kinase signaling pathways with constrained peptide scaffolds.TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradationsInteracting partners of FEN1 and its role in the development of anticancer therapeutics.β-Turn mimetic-based stabilizers of protein-protein interactions for the study of the non-canonical roles of leucyl-tRNA synthetase.The Hippo pathway in disease and therapy: cancer and beyondBioinformatic approaches to augment study of epithelial-to-mesenchymal transition in lung cancerEvolution of network biomarkers from early to late stage bladder cancer samples.Diffusion of information throughout the host interactome reveals gene expression variations in network proximity to target proteins of hepatitis C virus.Alternative RNA structure-coupled gene regulations in tumorigenesis.Focused chemical libraries--design and enrichment: an example of protein-protein interaction chemical space.Small-molecule inhibitors that target protein-protein interactions in the RAD51 family of recombinasesDARC 2.0: Improved Docking and Virtual Screening at Protein Interaction SitesState-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRsDevelopment of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors.A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis.Multiple target drug cocktail design for attacking the core network markers of four cancers using ligand-based and structure-based virtual screening methods.Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER).Computational Framework for Prediction of Peptide Sequences That May Mediate Multiple Protein Interactions in Cancer-Associated Hub Proteins.A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells.MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development.Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver FibrosisElucidating the druggable interface of protein-protein interactions using fragment docking and coevolutionary analysis.GEAR: A database of Genomic Elements Associated with drug Resistance.System level dynamics of post-translational modifications.Oncogenic protein interfaces: small molecules, big challenges.Towards developing biomarkers for glioblastoma multiforme: a proteomics view.Modulation of nociceptive ion channels and receptors via protein-protein interactions: implications for pain relief.Insights into the molecular mechanisms of action of bioportides: a strategy to target protein-protein interactions.ProteinsPlus: a web portal for structure analysis of macromolecules.Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitorsA three-gene signature from protein-protein interaction network of LOXL2- and actin-related proteins for esophageal squamous cell carcinoma prognosis.Self-assembling peptide-based building blocks in medical applications.Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer.
P2860
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P2860
Targeting protein-protein interactions as an anticancer strategy
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Targeting protein-protein interactions as an anticancer strategy
@ast
Targeting protein-protein interactions as an anticancer strategy
@en
Targeting protein-protein interactions as an anticancer strategy
@nl
type
label
Targeting protein-protein interactions as an anticancer strategy
@ast
Targeting protein-protein interactions as an anticancer strategy
@en
Targeting protein-protein interactions as an anticancer strategy
@nl
prefLabel
Targeting protein-protein interactions as an anticancer strategy
@ast
Targeting protein-protein interactions as an anticancer strategy
@en
Targeting protein-protein interactions as an anticancer strategy
@nl
P2093
P2860
P1476
Targeting protein-protein interactions as an anticancer strategy
@en
P2093
Andrei A Ivanov
Fadlo R Khuri
P2860
P304
P356
10.1016/J.TIPS.2013.04.007
P577
2013-05-29T00:00:00Z