Molecular and cellular biology of the human reduced folate carrier.
about
The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoterRestoration of high-level transport activity by human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier functionCrystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensisIdentification and characterization of an allosteric inhibitory site on dihydropteroate synthase.Targeting and trafficking of the human thiamine transporter-2 in epithelial cellsAppropriate nutrient supplementation in celiac diseaseIdentification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier.The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy numberGenes involved with folate uptake and distribution and their association with colorectal cancer risk.Xenopus reduced folate carrier regulates neural crest development epigenetically.The region between transmembrane domains 1 and 2 of the reduced folate carrier forms part of the substrate-binding pocket.Prevention of bone growth defects, increased bone resorption and marrow adiposity with folinic acid in rats receiving long-term methotrexate.Down syndrome and malignancies: a unique clinical relationship: a paper from the 2008 william beaumont hospital symposium on molecular pathologyReplacing sulfa drugs with novel DHPS inhibitorsResistance to antifolates.Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy.Gene-environment interactions and epigenetic pathways in autism: the importance of one-carbon metabolism.Characterization of a cysteine-less human reduced folate carrier: localization of a substrate-binding domain by cysteine-scanning mutagenesis and cysteine accessibility methods.Genome position and gene amplificationChemosensitization of Plasmodium falciparum by probenecid in vitro.Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans.Restoration of transport activity by co-expression of human reduced folate carrier half-molecules in transport-impaired K562 cells: localization of a substrate binding domain to transmembrane domains 7-12.Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function.The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism.Relationship of the reduced folate carrier gene polymorphism G80A to methotrexate plasma concentration, toxicity, and disease outcome in childhood acute lymphoblastic leukemia.Reduced folate carrier transports thiamine monophosphate: an alternative route for thiamine delivery into mammalian cells.A new type of high affinity folic acid transporter in the protozoan parasite Leishmania and deletion of its gene in methotrexate-resistant cells.Shaping of tumor and drug-resistant genomes by instability and selection.
P2860
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P2860
Molecular and cellular biology of the human reduced folate carrier.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Molecular and cellular biology of the human reduced folate carrier.
@ast
Molecular and cellular biology of the human reduced folate carrier.
@en
Molecular and cellular biology of the human reduced folate carrier.
@nl
type
label
Molecular and cellular biology of the human reduced folate carrier.
@ast
Molecular and cellular biology of the human reduced folate carrier.
@en
Molecular and cellular biology of the human reduced folate carrier.
@nl
prefLabel
Molecular and cellular biology of the human reduced folate carrier.
@ast
Molecular and cellular biology of the human reduced folate carrier.
@en
Molecular and cellular biology of the human reduced folate carrier.
@nl
P1476
Molecular and cellular biology of the human reduced folate carrier.
@en
P2093
L H Matherly
P304
P356
10.1016/S0079-6603(01)67027-2
P577
2001-01-01T00:00:00Z