Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte
about
A computational approach to understanding the cardiac electromechanical activation sequence in the normal and failing heart, with translation to the clinical practice of CRTPhospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy.Specification, construction, and exact reduction of state transition system models of biochemical processes.Models of cardiac electromechanics based on individual hearts imaging data: image-based electromechanical models of the heartMitochondrial calcium handling within the interstitial cells of Cajal.Models of cardiac excitation-contraction coupling in ventricular myocytesPhysiologic gating properties of unitary cardiac L-type Ca2+ channels.Cardiac resynchronization therapy improves altered Na channel gating in canine model of dyssynchronous heart failure.Ca2+ alternans in a cardiac myocyte model that uses moment equations to represent heterogeneous junctional SR Ca2+.Role of CaMKII in RyR leak, EC coupling and action potential duration: a computational model.Data-based theoretical identification of subcellular calcium compartments and estimation of calcium dynamics in cardiac myocytes.Stochastic hybrid modeling of intracellular calcium dynamics.Spontaneous Ca2+ sparks and Ca2+ homeostasis in a minimal model of permeabilized ventricular myocytes.Ionic mechanisms of cellular electrical and mechanical abnormalities in Brugada syndrome.Selective Na(+) /Ca(2+) exchanger inhibition prevents Ca(2+) overload-induced triggered arrhythmiasImaging the electromechanical activity of the heart in vivo.Integrative modeling of the cardiac ventricular myocyte.Inhibiting Na+/K+ ATPase can impair mitochondrial energetics and induce abnormal Ca2+ cycling and automaticity in guinea pig cardiomyocytes.Multi-scale computational models of familial hypertrophic cardiomyopathy: genotype to phenotype.Cardiac myocytes and local signaling in nano-domains.Kinetic properties of the cardiac L-type Ca2+ channel and its role in myocyte electrophysiology: a theoretical investigation.A probability density approach to modeling local control of calcium-induced calcium release in cardiac myocytes.A kinetic model for calcium dynamics in RAW 264.7 cells: 1. Mechanisms, parameters, and subpopulational variability.Toward an integrative computational model of the Guinea pig cardiac myocyte.Mitochondria in cardiomyocyte Ca2+ signaling.Roles of phosphodiesterases in the regulation of the cardiac cyclic nucleotide cross-talk signaling networkRyanodine receptor allosteric coupling and the dynamics of calcium sparksMoment closure for local control models of calcium-induced calcium release in cardiac myocytesCalsequestrin-mediated mechanism for cellular calcium transient alternansMechanisms of transmurally varying myocyte electromechanics in an integrated computational modelProperties of two human atrial cell models in tissue: restitution, memory, propagation, and reentry.From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scalesEffect of transmurally heterogeneous myocyte excitation-contraction coupling on canine left ventricular electromechanics.Integrative systems models of cardiac excitation-contraction coupling.Alternans and arrhythmias: from cell to heart.Dynamic local changes in sarcoplasmic reticulum calcium: physiological and pathophysiological roles.Decoding myocardial Ca²⁺ signals across multiple spatial scales: a role for sensitivity analysis.Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca2+ (mis)handling.Mechanisms of the cyclic nucleotide cross-talk signaling network in cardiac L-type calcium channel regulation.Neuronal sodium channels: emerging components of the nano-machinery of cardiac calcium cycling.
P2860
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P2860
Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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name
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@ast
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@en
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@nl
type
label
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@ast
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@en
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@nl
prefLabel
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@ast
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@en
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@nl
P2093
P2860
P1433
P1476
Mechanisms of excitation-contr ...... he cardiac ventricular myocyte
@en
P2093
Joseph L Greenstein
Raimond L Winslow
Robert Hinch
P2860
P356
10.1529/BIOPHYSJ.105.065169
P407
P577
2005-10-07T00:00:00Z