The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations
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Calmodulin-dependent protein kinase II: linking heart failure and arrhythmiasTowards a better understanding of QT interval variabilityCa(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequencesNew therapeutic targets in cardiology: arrhythmias and Ca2+/calmodulin-dependent kinase II (CaMKII)Determinants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: a computational analysisPopulation of computational rabbit-specific ventricular action potential models for investigating sources of variability in cellular repolarisationPhospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy.Protein structure networks.Synergy between CaMKII substrates and β-adrenergic signaling in regulation of cardiac myocyte Ca(2+) handling.Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytesSynchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias.A multiscale computational model of spatially resolved calcium cycling in cardiac myocytes: from detailed cleft dynamics to the whole cell concentration profiles.Using models of the myocyte for functional interpretation of cardiac proteomic data.Contributions of ion channel currents to ventricular action potential changes and induction of early afterdepolarizations during acute hypoxia.Natural inequalities: why some L-type Ca2+ channels work harder than othersIrregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos?Role of CaMKII in RyR leak, EC coupling and action potential duration: a computational model.Nonlinear and Stochastic Dynamics in the HeartMechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyteOrphaned ryanodine receptors in the failing heart.Chaos in the genesis and maintenance of cardiac arrhythmias.Repolarization Lability Measured by Spatial TT' AngleContribution of the Na+/Ca2+ exchanger to rapid Ca2+ release in cardiomyocytes.Integrative modeling of the cardiac ventricular myocyte.Beat-to-beat spatiotemporal variability in the T vector is associated with sudden cardiac death in participants without left ventricular hypertrophy: the Atherosclerosis Risk in Communities (ARIC) Study.Cardiac myocytes and local signaling in nano-domains.A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis.Rational strategy to stop arrhythmias: Early afterdepolarizations and L-type Ca2+ current.Protein geometry and placement in the cardiac dyad influence macroscopic properties of calcium-induced calcium release.Mechanistic Investigation of the Arrhythmogenic Role of Oxidized CaMKII in the HeartRole of the transient outward potassium current in the genesis of early afterdepolarizations in cardiac cells.Synchronization of early afterdepolarizations and arrhythmogenesis in heterogeneous cardiac tissue models.A strategy for integrative computational physiology.Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias.β-adrenergic stimulation activates early afterdepolarizations transiently via kinetic mismatch of PKA targets.Ca2+/calmodulin-dependent protein kinase II-dependent remodeling of Ca2+ current in pressure overload heart failure.QT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESC Working Group on Cardiac Cellular EleEvidence for the regulation of L-type Ca2+ channels in the heart by reactive oxygen species: mechanism for mediating pathology.Nonlinear dynamics in cardiology.Identification of Ikr kinetics and drug binding in native myocytes.
P2860
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P2860
The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The role of stochastic and mod ...... on early after-depolarizations
@ast
The role of stochastic and mod ...... on early after-depolarizations
@en
type
label
The role of stochastic and mod ...... on early after-depolarizations
@ast
The role of stochastic and mod ...... on early after-depolarizations
@en
prefLabel
The role of stochastic and mod ...... on early after-depolarizations
@ast
The role of stochastic and mod ...... on early after-depolarizations
@en
P2093
P2860
P1433
P1476
The role of stochastic and mod ...... on early after-depolarizations
@en
P2093
Antti J Tanskanen
Brian O'Rourke
Raimond L Winslow
P2860
P356
10.1529/BIOPHYSJ.104.051508
P407
P577
2004-10-22T00:00:00Z