CRISPR-mediated direct mutation of cancer genes in the mouse liver
about
CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseasesSomatic mutations in disorders with disrupted brain connectivityIn Vivo Delivery Systems for Therapeutic Genome EditingBrain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the futureThe Rise of CRISPR/Cas for Genome Editing in Stem CellsEmerging Technologies to Create Inducible and Genetically Defined Porcine Cancer ModelsMaking sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genomeGenome Editing and Its Applications in Model OrganismsBeyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogationAnimal Models for Fibrotic Liver Diseases: What We Have, What We Need, and What Is under DevelopmentGEMMs as preclinical models for testing pancreatic cancer therapiesCRISPR-Cas9: A Revolutionary Tool for Cancer ModellingApplication Progress of CRISPR/Cas9 System for Gene Editing in Tumor ResearchThe CRISPR revolution and its impact on cancer researchAdvances in CRISPR-Cas9 genome engineering: lessons learned from RNA interferenceEpigenome engineering in cancer: fairytale or a realistic path to the clinic?CRISPR-Cas9 delivery to hard-to-transfect cells via membrane deformationCRISPR-Cas9: from Genome Editing to Cancer ResearchPatterns of CRISPR/Cas9 activity in plants, animals and microbesSurvival and Evolution of CRISPR-Cas System in Prokaryotes and Its ApplicationsGenetically engineered mouse models in oncology research and cancer medicineLiver-targeted gene therapy: Approaches and challengesThe CRISPR system can correct or modify the expression of genes responsible for hereditary diseasesEnhancing Targeted Genomic DNA Editing in Chicken Cells Using the CRISPR/Cas9 SystemGenetic manipulation of reptilian embryos: toward an understanding of cortical development and evolutionCRISPR-Cas9 knockin mice for genome editing and cancer modelingExpressed Structurally-stable Inverted Duplicates in Mammalian Genomes as Functional Noncoding ElementsCRISPR/Cas9: Transcending the Reality of Genome Editing.Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivoLong-Term Assessment of AAV-Mediated Zinc Finger Nuclease Expression in the Mouse Brain.CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice.CRISPR/Cas9: From Genome Engineering to Cancer Drug DiscoveryGeneration and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.The potential of the combination of CRISPR/Cas9 and pluripotent stem cells to provide human organs from chimaeric pigs.Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma.Inducible in vivo genome editing with CRISPR-Cas9Applications of the CRISPR-Cas9 system in cancer biology.Precision cancer mouse models through genome editing with CRISPR-Cas9.CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.
P2860
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P2860
CRISPR-mediated direct mutation of cancer genes in the mouse liver
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@ast
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@en
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@nl
type
label
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@ast
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@en
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@nl
prefLabel
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@ast
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@en
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@nl
P2093
P2860
P50
P356
P1433
P1476
CRISPR-mediated direct mutation of cancer genes in the mouse liver
@en
P2093
Daniel G Anderson
Denise G Crowley
Feng Zhang
Gillian Yang
Phillip A Sharp
Roderick Bronson
Thales Papagiannakopoulos
Tyler Jacks
P2860
P2888
P304
P356
10.1038/NATURE13589
P407
P577
2014-08-06T00:00:00Z
P5875
P6179
1030048072