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An Overview of CRISPR-Based Tools and Their Improvements: New Opportunities in Understanding Plant-Pathogen Interactions for Better Crop ProtectionGenome Editing and Its Applications in Model OrganismsApplications of CRISPR-Cas systems in neuroscienceColorectal cancer models for novel drug discoveryThe CRISPR revolution and its impact on cancer researchPreclinical mouse cancer models: a maze of opportunities and challenges.Using CRISPR/Cas to study gene function and model disease in vivoGenetically engineered mouse models in oncology research and cancer medicineRapid Evolution of Manifold CRISPR Systems for Plant Genome EditingApplications of Cas9 as an RNA-programmed RNA-binding proteinA Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene RegulationLigand-binding domains of nuclear receptors facilitate tight control of split CRISPR activityA Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse Heart.CRISPR/Cas9: Transcending the Reality of Genome Editing.CRISPR/Cas9: From Genome Engineering to Cancer Drug DiscoveryGenetic and epigenetic control of gene expression by CRISPR-Cas systems.R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestineApplications of the CRISPR-Cas9 system in cancer biology.Precision cancer mouse models through genome editing with CRISPR-Cas9.Photoactivatable CRISPR-Cas9 for optogenetic genome editing.Conditional Control of CRISPR/Cas9 Function.Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switchApplications of CRISPR technologies in research and beyond.A chemical-inducible CRISPR-Cas9 system for rapid control of genome editing.Programmable RNA Tracking in Live Cells with CRISPR/Cas9.Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.Cas9 gRNA engineering for genome editing, activation and repression.A general strategy to construct small molecule biosensors in eukaryotes.CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataractsImprovement of the reverse tetracycline transactivator by single amino acid substitutions that reduce leaky target gene expression to undetectable levels.The Development of a Viral Mediated CRISPR/Cas9 System with Doxycycline Dependent gRNA Expression for Inducible In vitro and In vivo Genome Editing.Genomic Disruption of VEGF-A Expression in Human Retinal Pigment Epithelial Cells Using CRISPR-Cas9 Endonuclease.An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targetingLoss-of-function genetic tools for animal models: cross-species and cross-platform differences.Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering.Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilizationHow to Train a Cell-Cutting-Edge Molecular Tools.Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease.Apolipoprotein E as a Therapeutic Target in Alzheimer's Disease: A Review of Basic Research and Clinical Evidence
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Inducible in vivo genome editing with CRISPR-Cas9
@ast
Inducible in vivo genome editing with CRISPR-Cas9
@en
Inducible in vivo genome editing with CRISPR-Cas9
@nl
type
label
Inducible in vivo genome editing with CRISPR-Cas9
@ast
Inducible in vivo genome editing with CRISPR-Cas9
@en
Inducible in vivo genome editing with CRISPR-Cas9
@nl
prefLabel
Inducible in vivo genome editing with CRISPR-Cas9
@ast
Inducible in vivo genome editing with CRISPR-Cas9
@en
Inducible in vivo genome editing with CRISPR-Cas9
@nl
P2093
P2860
P356
P1433
P1476
Inducible in vivo genome editing with CRISPR-Cas9
@en
P2093
Ashlesha Muley
Darjus F Tschaharganeh
Edward R Kastenhuber
Geulah Livshits
Jonathan Fisher
Kevin P O'Rourke
Lukas E Dow
Nicholas D Socci
Scott W Lowe
P2860
P2888
P304
P356
10.1038/NBT.3155
P577
2015-02-18T00:00:00Z
P5875
P6179
1016529049