Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor. - Wikidata - awgldk - TriplyDB

Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor.

Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor.

http://www.wikidata.org/entity/Q34353797

about

GPR50 is the mammalian ortholog of Mel1c: evidence of rapid evolution in mammals The genetics of bipolar disorder: genome ‘hot regions,’ genes, new potential candidates and future directions The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization A Review of Melatonin, Its Receptors and Drugs Sex chromosome abnormalities and psychiatric diseases Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia New therapeutic targets for mood disorders Bipolar disorder: candidate drug targets.Genome-wide association study of copy number variations (CNVs) with opioid dependence.Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice.Poor replication of candidate genes for major depressive disorder using genome-wide association data.Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population.Association study of CSF2RB with schizophrenia in Irish family and case - control samples.GPR50 interacts with TIP60 to modulate glucocorticoid receptor signalling.Laser-capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus.Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels.New targets for rapid antidepressant action.Meta-analyses of genetic studies on major depressive disorder.Comparing genes and phenomenology in the major psychoses: schizophrenia and bipolar 1 disorder.Sex-specific rates of transmission of psychosis in the New England high-risk family study.Involvement of GPR50 polymorphisms in depression: independent replication in a prospective elderly cohort.Hunting for the function of orphan GPCRs - beyond the search for the endogenous ligand.The pattern of melatonin receptor expression in the brain may influence antidepressant treatment Melatonin in aging and disease -multiple consequences of reduced secretion, options and limits of treatment.Developmental expression of orphan G protein-coupled receptor 50 in the mouse brain.Genetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets.Molecular genetics of bipolar disorder and depression.Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?Melatonin receptor genes in vertebrates.Induction of the metabolic regulator Txnip in fasting-induced and natural torpor.Incomplete coverage of candidate genes: a poorly considered bias.Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia?Sex differences in the genetic risk for schizophrenia: history of the evidence for sex-specific and sex-dependent effects.Toward the next step in G protein-coupled receptor research: a knowledge-driven analysis for the next potential targets in drug discovery.Neuro-psychopharmacological perspective of Orphan receptors of Rhodopsin (class A) family of G protein-coupled receptors.Neuroanatomical distribution of the orphan GPR50 receptor in adult sheep and rodent brains.Detection of the human GPR50 orphan seven transmembrane protein by polyclonal antibodies mapping different epitopes.Currently recognized genes for schizophrenia: High-resolution chromosome ideogram representation.Interleukin 3 and schizophrenia: the impact of sex and family history.Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.

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P2860

Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor.

http://www.wikidata.org/entity/Q34353797

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P2860

Cloning of a melatonin-related receptor from human pituitary

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor

Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder

Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

Association between a polymorphism in the pseudoautosomal X-linked gene SYBL1 and bipolar affective disorder

A critical analysis of data presented in eight studies favouring X-linkage of bipolar illness with special emphasis on formal genetic aspects.

G-protein coupled receptor kinases as modulators of G-protein signalling.

A first-generation X-inactivation profile of the human X chromosome.

Genetic epidemiology of major depression: review and meta-analysis.

"Cade's disease" and beyond: misdiagnosis, antidepressant use, and a proposed definition for bipolar spectrum disorder.

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