Both mucosal and systemic routes of immunization with the live, attenuated NYVAC/simian immunodeficiency virus SIV(gpe) recombinant vaccine result in gag-specific CD8(+) T-cell responses in mucosal tissues of macaques.
about
Mucosal HIV transmission and vaccination strategies through oral compared with vaginal and rectal routesNonhuman primate models for HIV/AIDS vaccine developmentThe evolution of poxvirus vaccinesChallenges in mucosal HIV vaccine development: lessons from non-human primate modelsThe development of an AIDS mucosal vaccine.Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus.Induction of Potent and Long-Lived Antibody and Cellular Immune Responses in the Genitorectal Mucosa Could be the Critical Determinant of HIV Vaccine Efficacy.Dynamic T cell migration program provides resident memory within intestinal epitheliumThe influence of delivery vectors on HIV vaccine efficacyLong-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization.Menstrual blood as a potential source of endometrial derived CD3+ T cells.Both systemic and mucosal LCMV immunization generate robust viral-specific IgG in mucosal secretions, but elicit poor LCMV-specific IgA.The efficacy of T cell-mediated immune responses is reduced by the envelope protein of the chimeric HIV-1/SIV-KB9 virus in vivo.Systemic immunization with an ALVAC-HIV-1/protein boost vaccine strategy protects rhesus macaques from CD4+ T-cell loss and reduces both systemic and mucosal simian-human immunodeficiency virus SHIVKU2 RNA levels.HIV infection and the gastrointestinal immune systemDurable mucosal simian immunodeficiency virus-specific effector memory T lymphocyte responses elicited by recombinant adenovirus vectors in rhesus monkeysAbility of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virusImpact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa.Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challengeIntranasal delivery of vaccines against HIV.Human immunodeficiency virus type 1 vaccine development: recent advances in the cytotoxic T-lymphocyte platform "spotty business".The dynamic lives of T cells: new approaches and themesAerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenicSystemic and mucosal infection program protective memory CD8 T cells in the vaginal mucosa.DNA-MVA vaccine protection after X4 SHIV challenge in macaques correlates with day-of-challenge antiviral CD4+ cell-mediated immunity levels and postchallenge preservation of CD4+ T cell memory.Translational Mini-Review Series on Vaccines for HIV: T lymphocyte trafficking and vaccine-elicited mucosal immunity.HIV vaccine research and discovery in the nonhuman primates model: a unified theory in acquisition prevention and control of SIV infectionTissue competence imprinting and tissue residency of CD8 T cellsMembrane-anchored CCL20 augments HIV Env-specific mucosal immune responses.Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.Route of adenovirus-based HIV-1 vaccine delivery impacts the phenotype and trafficking of vaccine-elicited CD8+ T lymphocytes.Recombinant Mycobacterium bovis bacillus Calmette-Guérin vectors prime for strong cellular responses to simian immunodeficiency virus gag in rhesus macaques.Systemic vaccination induces clonally diverse SIV-specific CD8+ T-cell populations in systemic and mucosal compartments.Systemic vaccination prevents the total destruction of mucosal CD4 T cells during acute SIV challenge.Emerging Targets for Developing T Cell-Mediated Vaccines for Human Immunodeficiency Virus (HIV)-1.CD4+ T-cell loss and delayed expression of modulators of immune responses at mucosal sites of vaccinated macaques following SIV(mac251) infection.Nasal delivery of PLG microparticle encapsulated defensin peptides adjuvanted gp41 antigen confers strong and long-lasting immunoprotective response against HIV-1.Multiprotein genetic vaccine in the SIV-Macaca animal model: a promising approach to generate sterilizing immunity to HIV infection.
P2860
Q22241377-A64674C4-76DE-4038-BF4E-5CAF93B2C098Q26861148-BA1B8B63-CB48-4DCB-9211-9DE3B9DA3083Q26995905-B8D90642-FF6D-4D51-8128-4CE5262FE34FQ27022152-A2578B7C-D44C-4FF6-BFC4-463930B2BB24Q30408103-10829C24-4179-477A-A6BF-F9082B8FC7A1Q33379075-BF30CF9E-4201-4725-95F8-70CC91FBB781Q33611645-C33F649F-54B5-4EA4-BEE1-9DF14E5EE36BQ33730150-781E0E85-9677-42E5-91AA-ED88CC89F151Q34077543-70A682CB-5012-4D93-8EC9-397E17FBE0D6Q34099837-D23F3155-4685-47AA-970E-038FC2634E96Q34103466-4F23BA70-B498-42FD-AEDA-04EB356E69D8Q34296797-7961C566-CCAF-4770-9E0E-84C8EA42E7A1Q34535707-ACA74E72-9BA7-4BE3-B2F0-D2D091C8658DQ34546037-32BE8D65-3278-48A3-ACDC-A0A1241C61F0Q34601874-0E2DDAE0-BA3B-4A02-A89B-82104708C248Q35363320-E3762DE8-3658-44EA-8053-00F8FA9CBDD2Q35675044-DEDC5344-BA2B-4692-8663-70F93EF1B6BFQ35849596-393010D9-1892-4065-8E04-90E51B476E82Q36228649-60A7285F-26F2-44FF-8928-94AF3202BDE0Q36409054-6BB90423-1D59-4EA9-8AF2-7A4A7D56E568Q36498186-496F8071-FD0A-45E5-9814-446FF36B331FQ36589038-72441393-8C7E-4290-8CC9-E2319FD90B40Q36883057-7E5292D4-BAB4-44B2-9DC6-5F44B3E72B67Q37111062-7BBE60C7-0FBF-449E-A349-3EFED54CA47EQ37181874-CA406B17-5B8B-4A7A-B6AD-5B69AEBA18A2Q37552013-5A62F6A9-3118-403C-91FD-961AECA28D93Q38105946-8431878F-F484-49FC-8F5C-6B096CCE2EDAQ38142101-4DFA7343-73C3-4DB6-AC83-063B0BDBBCBDQ38613574-D4515721-810B-44DB-A791-5A0513FF8B5AQ40113278-34D671D2-8184-4FA6-AEA8-232F2F43F810Q40757700-ABCA8E33-91D2-4FB6-9C1F-7F04E05C74F0Q42015551-D48B568A-0C16-4A2B-9BCF-F0370607BBB8Q42657266-3252072D-9966-40FF-B62F-96F66EA1931EQ44097571-1AFB0C49-3AB5-456B-936B-BE9A8908200DQ45325097-E5F2B874-1D34-420F-BE92-26BD4EA93770Q46200257-1D00037B-0C75-473F-B3AA-B35AC582E65CQ50999753-03D19EA1-6B71-4DFD-8AAA-BD476E486C90Q53536913-C279E0D7-B8FF-44AB-BA32-67A91BF13139
P2860
Both mucosal and systemic routes of immunization with the live, attenuated NYVAC/simian immunodeficiency virus SIV(gpe) recombinant vaccine result in gag-specific CD8(+) T-cell responses in mucosal tissues of macaques.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@ast
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@en
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@nl
type
label
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@ast
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@en
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@nl
prefLabel
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@ast
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@en
Both mucosal and systemic rout ...... n mucosal tissues of macaques.
@nl
P2093
P2860
P921
P1433
P1476
Both mucosal and systemic rout ...... in mucosal tissues of macaques
@en
P2093
Andrew A Lackner
Brian Kelsall
Genoveffa Franchini
Janos Nacsa
Jim Tartaglia
Liljana Stevceva
Warren Strober
Xavier Alvarez
P2860
P304
11659-11676
P356
10.1128/JVI.76.22.11659-11676.2002
P407
P577
2002-11-01T00:00:00Z