Tethered agonist analogs as site-specific probes for domains of the human α7 nicotinic acetylcholine receptor that differentially regulate activation and desensitization.
about
Nicotine: specific role in angiogenesis, proliferation and apoptosis.The effective opening of nicotinic acetylcholine receptors with single agonist binding sitesPositive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations.Investigation of the molecular mechanism of the α7 nicotinic acetylcholine receptor positive allosteric modulator PNU-120596 provides evidence for two distinct desensitized states.Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptorCritical Molecular Determinants of α7 Nicotinic Acetylcholine Receptor Allosteric Activation: SEPARATION OF DIRECT ALLOSTERIC ACTIVATION AND POSITIVE ALLOSTERIC MODULATION.Covalent trapping of methyllycaconitine at the α4-α4 interface of the α4β2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed.The activity of GAT107, an allosteric activator and positive modulator of α7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface.Persistent activation of α7 nicotinic ACh receptors associated with stable induction of different desensitized states.Orthosteric and allosteric potentiation of heteromeric neuronal nicotinic acetylcholine receptors.Trapping of ivermectin by a pentameric ligand-gated ion channel upon open-to-closed isomerization.Silent, fluorescent labeling of native neuronal receptors.
P2860
Q34229828-9218FE07-0B41-4610-81B8-EF846EC87CE7Q34745010-445DFB65-3991-47FF-916A-B2539CFCC098Q35182164-65829CCD-71F4-4F16-AF5D-51EF496341F8Q35586093-1F5836C8-F3A9-4ACA-9E70-15A2D4561AA3Q36052452-D51684B8-8A69-4354-86BC-CFFE0120308CQ36650296-8AC36648-BA76-42FC-A49A-0FD97A0C6D9CQ37168375-27100922-083D-4D28-A573-D9DDFD2D5A64Q37583624-5270B977-011F-4C71-A784-D0797C89B077Q38801002-3344636D-436D-42B8-A221-AB01CEC9DBD7Q39136644-EEDA686C-50B0-4D28-80DA-14D4E759DBD3Q41786836-EF65209D-F527-4891-9126-0231A499B31FQ48913104-C1649196-E3EC-4A17-BB42-3E2EBFE1DC8B
P2860
Tethered agonist analogs as site-specific probes for domains of the human α7 nicotinic acetylcholine receptor that differentially regulate activation and desensitization.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Tethered agonist analogs as si ...... ctivation and desensitization.
@ast
Tethered agonist analogs as si ...... ctivation and desensitization.
@en
Tethered agonist analogs as si ...... ctivation and desensitization.
@nl
type
label
Tethered agonist analogs as si ...... ctivation and desensitization.
@ast
Tethered agonist analogs as si ...... ctivation and desensitization.
@en
Tethered agonist analogs as si ...... ctivation and desensitization.
@nl
prefLabel
Tethered agonist analogs as si ...... ctivation and desensitization.
@ast
Tethered agonist analogs as si ...... ctivation and desensitization.
@en
Tethered agonist analogs as si ...... ctivation and desensitization.
@nl
P2093
P2860
P356
P1476
Tethered agonist analogs as si ...... ctivation and desensitization.
@en
P2093
Clare Stokes
Jingyi Wang
Nicole A Horenstein
Roger L Papke
P2860
P304
P356
10.1124/MOL.110.066662
P577
2010-09-07T00:00:00Z