Pausing during reverse transcription increases the rate of retroviral recombination
about
RNase H activity: structure, specificity, and function in reverse transcriptionInfluence of vector design and host cell on the mechanism of recombination and emergence of mutant subpopulations of replicating retroviral vectors.A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro.Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element.Factors that determine the efficiency of HIV-1 strand transfer initiated at a specific siteComparison of SIV and HIV-1 genomic RNA structures reveals impact of sequence evolution on conserved and non-conserved structural motifs.Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4Mechanisms and factors that influence high frequency retroviral recombinationTy1 reverse transcriptase does not read through the proposed 2',5'-branched retrotransposition intermediate in vitroSubstitution of alanine for tyrosine-64 in the fingers subdomain of M-MuLV reverse transcriptase impairs strand displacement synthesis and blocks viral replication in vivo.The remarkable frequency of human immunodeficiency virus type 1 genetic recombinationSequence determinants of breakpoint location during HIV-1 intersubtype recombination.Effects of identity minimization on Moloney murine leukemia virus template recognition and frequent tertiary template-directed insertions during nonhomologous recombination.Hairpin-induced tRNA-mediated (HITME) recombination in HIV-1.Arm-specific cleavage and mutation during reverse transcription of 2΄,5΄-branched RNA by Moloney murine leukemia virus reverse transcriptaseReduced dNTP interaction of human immunodeficiency virus type 1 reverse transcriptase promotes strand transfer.Insights into the multiple roles of pausing in HIV-1 reverse transcriptase-promoted strand transfers.Mechanisms that prevent template inactivation by HIV-1 reverse transcriptase RNase H cleavages.Generation and characterization of new highly thermostable and processive M-MuLV reverse transcriptase variants.
P2860
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P2860
Pausing during reverse transcription increases the rate of retroviral recombination
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
Pausing during reverse transcription increases the rate of retroviral recombination
@ast
Pausing during reverse transcription increases the rate of retroviral recombination
@en
Pausing during reverse transcription increases the rate of retroviral recombination
@nl
type
label
Pausing during reverse transcription increases the rate of retroviral recombination
@ast
Pausing during reverse transcription increases the rate of retroviral recombination
@en
Pausing during reverse transcription increases the rate of retroviral recombination
@nl
prefLabel
Pausing during reverse transcription increases the rate of retroviral recombination
@ast
Pausing during reverse transcription increases the rate of retroviral recombination
@en
Pausing during reverse transcription increases the rate of retroviral recombination
@nl
P2860
P1433
P1476
Pausing during reverse transcription increases the rate of retroviral recombination
@en
P2093
Christian Lanciault
James J Champoux
P2860
P304
P356
10.1128/JVI.80.5.2483-2494.2006
P407
P577
2006-03-01T00:00:00Z