The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family.
about
The evolution of vertebrate opioid receptorsBuprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically activeBuprenorphine: a unique drug with complex pharmacologySmall-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): ligand-based analysis of structural factors influencing intrinsic activity at NOPPharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in miceFunctional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonistsStructural insights into ligand recognition and selectivity for classes A, B, and C GPCRsThe nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medicationsNociceptin produces antinociception after spinal administration in amphibiansSynaptic effects induced by alcohol.Endogenous Opioids: The Downside of Opposing Stress.Endogenous opioids: opposing stress with a cost.The role of orphanin FQ/nociceptin in neuroplasticity: relationship to stress, anxiety and neuroinflammation.Stimulation of sensory neuropeptide release by nociceptin/orphanin FQ leads to hyperaemia in acutely inflamed rat knees.Nociceptin/orphanin FQ suppresses adaptive immune responses in vivo and at picomolar levels in vitro.Role of opioid receptor like-1 receptor in modulation of endocrine, immunological, and behavioral responses to the T-cell superantigen staphylococcal enterotoxin ADesigning bifunctional NOP receptor-mu opioid receptor ligands from NOP-receptor selective scaffolds. Part II.Effects of nociceptin/orphanin FQ on rats with cathartic colonModulation of silent and constitutively active nociceptin/orphanin FQ receptors by potent receptor antagonists and Na+ ions in rat sympathetic neurons.Low utility of plasma Nociceptin/orphanin FQ in the diagnosis of hepatocellular carcinoma.Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111.A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies.The Nociceptin Receptor as an Emerging Molecular Target for Cocaine AddictionBuprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor systemThe endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine.Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide (NOP) receptors with positron emission tomographyInflammatory mediators influence the expression of nociceptin and its receptor in human whole blood cultures.Comparison of the ORL1 receptor-mediated inhibition of noradrenaline release in human and rat neocortical slices[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.Direct and indirect inhibition by nociceptin/orphanin FQ on noradrenaline release from rodent cerebral cortex in vitroPharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortexActivation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux.Oligodendrocyte responses to buprenorphine uncover novel and opposing roles of μ-opioid- and nociceptin/orphanin FQ receptors in cell development: implications for drug addiction treatment during pregnancyNOP Receptor Ligands as Potential Agents for Inflammatory and Autoimmune Diseases.Orphanin FQ/nociceptin interacts with the basolateral amygdala noradrenergic system in memory consolidation.Nociceptin/orphanin FQ blocks the antinociception induced by mu, kappa and delta opioid agonists on the cold water tail-flick test.Knock-In Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization.In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptorQuantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor.Serine 363 is required for nociceptin/orphanin FQ opioid receptor (NOPR) desensitization, internalization, and arrestin signaling.
P2860
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P2860
The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The molecular and behavioral p ...... n peptide and receptor family.
@ast
The molecular and behavioral p ...... n peptide and receptor family.
@en
The molecular and behavioral p ...... n peptide and receptor family.
@nl
type
label
The molecular and behavioral p ...... n peptide and receptor family.
@ast
The molecular and behavioral p ...... n peptide and receptor family.
@en
The molecular and behavioral p ...... n peptide and receptor family.
@nl
prefLabel
The molecular and behavioral p ...... n peptide and receptor family.
@ast
The molecular and behavioral p ...... n peptide and receptor family.
@en
The molecular and behavioral p ...... n peptide and receptor family.
@nl
P1476
The molecular and behavioral p ...... n peptide and receptor family.
@en
P2093
G W Pasternak
P304
P577
2001-09-01T00:00:00Z