The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine. - Wikidata - awgldk - TriplyDB

The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine.

The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine.

http://www.wikidata.org/entity/Q34725890

about

The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications The Nociceptin Receptor as an Emerging Molecular Target for Cocaine Addiction The first universal opioid ligand, (2S)-2-[(5R,6R,7R,14S)-N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]-3,3-dimethylpentan-2-ol (BU08028): characterization of the in vitro profile and in vivo behavioral effects in mous Differential pharmacological actions of methadone and buprenorphine in human embryonic kidney 293 cells coexpressing human μ-opioid and opioid receptor-like 1 receptors.Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor.The rewarding action of acute cocaine is reduced in β-endorphin deficient but not in μ opioid receptor knockout mice Buprenorphine-elicited alteration of adenylate cyclase activity in human embryonic kidney 293 cells coexpressing κ-, μ-opioid and nociceptin receptors.Stress-related neuropeptides and addictive behaviors: beyond the usual suspects.Nociceptin receptor activation does not alter acquisition, expression, extinction and reinstatement of conditioned cocaine preference in mice A neuropeptide-centric view of psychostimulant addiction Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.Estradiol: a key biological substrate mediating the response to cocaine in female rats The role of NOP receptors in psychomotor stimulation and locomotor sensitization induced by cocaine and amphetamine in mice Buprenorphine requires concomitant activation of NOP and MOP receptors to reduce cocaine consumption.Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction.Usefulness of knockout mice to clarify the role of the opioid system in chronic pain.Alterations in the level of OFQ/N-IR in rat brain regions by cocaine.Novel role of the nociceptin system as a regulator of glutamate transporter expression in developing astrocytes.Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors.A systematic review of the role of the nociceptin receptor system in stress, cognition, and reward: relevance to schizophrenia.

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P2860

The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine.

http://www.wikidata.org/entity/Q34725890

description

2007 nî lūn-bûn

@nan

2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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type

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The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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prefLabel

The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

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J.NEUROPHARM.2007.11.003

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Neuropharmacology

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The endogenous OFQ/N/ORL-1 rec ...... ding effects of acute cocaine.

@en

P2093

Abdul Hamid

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Alexander T Nguyen

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Kabirullah Lutfy

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Paul Marquez

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P2860

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397)

Orphanin FQ/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in rats

Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor.

Conditioned place preference: what does it add to our preclinical understanding of drug reward?

The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family.

The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism.

Differential involvement of enkephalins in analgesic tolerance, locomotor sensitization, and conditioned place preference induced by morphine

Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats

Orphanin FQ/nociceptin suppresses motor activity through an action along the mesoaccumbens axis in rats

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564-568

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scholarly article

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10.1016/J.NEUROPHARM.2007.11.003

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3

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54

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2007-11-17T00:00:00Z

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5765556

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18082848

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2276976

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