Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm.
about
PhosphoregDB: the tissue and sub-cellular distribution of mammalian protein kinases and phosphatases.Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IVActivity-dependent transport of the transcriptional coactivator CRTC1 from synapse to nucleusSIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent processAnalysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members.Molecular and anatomical signatures of sleep deprivation in the mouse brainAMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB.CRTC2 complex by orphan nuclear receptor small heterodimer partner.The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser358 in adipocytesInvolvement of SIK3 in glucose and lipid homeostasis in mice.Transcription control pathways decode patterned synaptic inputs into diverse mRNA expression profilesSalt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.Role of salt-inducible kinase 1 in the activation of MEF2-dependent transcription by BDNFFinding gene regulatory network candidates using the gene expression knowledge base.A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells.Stimulation of StAR expression by cAMP is controlled by inhibition of highly inducible SIK1 via CRTC2, a co-activator of CREB.Salt-inducible kinase is involved in the regulation of corticotropin-releasing hormone transcription in hypothalamic neurons in rats.Activation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein.Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.Renal proximal tubule Na,K-ATPase is controlled by CREB-regulated transcriptional coactivators as well as salt-inducible kinase 1.Transcriptional regulation of episodic glucocorticoid secretionPterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.Transcriptional regulation of adrenocortical steroidogenic gene expression.The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.Multiple Signaling Pathways Coordinate CYP17 Gene Expression in the Human Adrenal CortexSIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes.PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway.Induction of melanogenesis by 4'-O-methylated flavonoids in B16F10 melanoma cells.Downregulation of SIK2 expression promotes the melanogenic program in mice.Phosphorylation of the CREB-specific coactivator TORC2 at Ser(307) regulates its intracellular localization in COS-7 cells and in the mouse liver.Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells.Involvement of SIK2/TORC2 signaling cascade in the regulation of insulin-induced PGC-1alpha and UCP-1 gene expression in brown adipocytes.14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs).Phosphoproteomics of cAMP signaling of Bordetella adenylate cyclase toxin in mouse dendritic cells.Epilepsy-causing sequence variations in SIK1 disrupt synaptic activity response gene expression and affect neuronal morphology.α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis.Current knowledge on the acute regulation of steroidogenesis
P2860
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P2860
Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@ast
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@en
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@nl
type
label
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@ast
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@en
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@nl
prefLabel
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@ast
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@en
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@nl
P2093
P2860
P1433
P1476
Salt-inducible kinase-1 repres ...... nucleus and in the cytoplasm.
@en
P2093
Hiroshi Takemori
Masaaki Muraoka
Mitsuhiro Okamoto
Nanao Horike
Yoshiko Katoh
P2860
P304
P356
10.1111/J.1432-1033.2004.04372.X
P407
P577
2004-11-01T00:00:00Z