The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
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High expression of HEF1 predicts a poorer prognosis of hepatocellular carcinoma: A retrospective study.Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseasesCAS proteins in health and disease: an updateNEDD9 promotes lung cancer metastasis through epithelial-mesenchymal transitionOncogenic herpesvirus KSHV Hijacks BMP-Smad1-Id signaling to promote tumorigenesisBioinformatic approaches to augment study of epithelial-to-mesenchymal transition in lung cancerTP53 transcription factor for the NEDD9/HEF1/Cas-L gene: potential targets in Non-Small Cell Lung Cancer treatment.LKB1 represses focal adhesion kinase (FAK) signaling via a FAK-LKB1 complex to regulate FAK site maturation and directional persistenceAberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers.cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth.Dysregulation of mTOR activity through LKB1 inactivation.VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex.A herpes simplex virus type 2-encoded microRNA promotes tumor cell metastasis by targeting suppressor of cytokine signaling 2 in lung cancer.Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells.Involvement of NEDD9 in the invasion and migration of gastric cancer.LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT.LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies.Deregulation of CRTCs in Aging and Age-Related Disease Risk.The MZF1/c-MYC axis mediates lung adenocarcinoma progression caused by wild-type lkb1 loss.MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy.Dysregulated CRTC1 activity is a novel component of PGE2 signaling that contributes to colon cancer growth.LKB1 loss at transcriptional level promotes tumor malignancy and poor patient outcomes in colorectal cancer.
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P2860
The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 October 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
@en
The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
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label
The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
@en
The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
@nl
prefLabel
The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
@en
The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
@nl
P2093
P2860
P1433
P1476
The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
@en
P2093
Haiquan Chen
Hongbin Ji
Hongyan Liu
Nabeel Bardeesy
Qiwei Zhai
Xiaolong Liu
P2860
P304
P356
10.1158/0008-5472.CAN-12-1909
P407
P577
2012-10-16T00:00:00Z