HEXIM1 targets a repeated GAUC motif in the riboregulator of transcription 7SK and promotes base pair rearrangements - Wikidata - awgldk - TriplyDB

HEXIM1 targets a repeated GAUC motif in the riboregulator of transcription 7SK and promotes base pair rearrangements

HEXIM1 targets a repeated GAUC motif in the riboregulator of transcription 7SK and promotes base pair rearrangements

http://www.wikidata.org/entity/Q34368113

about

7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK.Reconstitution of a functional 7SK snRNP Genetic analysis of the structure and function of 7SK small nuclear ribonucleoprotein (snRNP) in cells.A fully enzymatic method for site-directed spin labeling of long RNA.A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat RNA polymerase II transcription elongation control.Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.The Bin3 RNA methyltransferase targets 7SK RNA to control transcription and translation An evolutionary conserved Hexim1 peptide binds to the Cdk9 catalytic site to inhibit P-TEFb Solution structure of the 5'-terminal hairpin of the 7SK small nuclear RNA.A single point mutation in cyclin T1 eliminates binding to Hexim1, Cdk9 and RNA but not to AFF4 and enforces repression of HIV transcription.Detailed Secondary Structure Models of Invertebrate 7SK RNAs.Hexim1, an RNA-controlled protein hub.HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry

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P2860

HEXIM1 targets a repeated GAUC motif in the riboregulator of transcription 7SK and promotes base pair rearrangements

http://www.wikidata.org/entity/Q34368113

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@ast

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@en

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@nl

type

label

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@ast

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@en

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@nl

prefLabel

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@ast

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@en

HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@nl

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Nucleic Acids Research

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HEXIM1 targets a repeated GAUC ...... motes base pair rearrangements

@en

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A Durand

http://www.w3.org/2001/XMLSchema#string

Anne-Catherine Dock-Bregeon

http://www.w3.org/2001/XMLSchema#string

B Kieffer

http://www.w3.org/2001/XMLSchema#string

D Martinez-Zapien

http://www.w3.org/2001/XMLSchema#string

Isabelle Lebars

http://www.w3.org/2001/XMLSchema#string

J Coutant

http://www.w3.org/2001/XMLSchema#string

P2860

Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression

The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation

A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb

Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor

Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function

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7749-7763

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scholarly article

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10.1093/NAR/GKQ660

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21

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38

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2010-07-31T00:00:00Z

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45440588

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20675720

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2995076

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