SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
about
TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradationThe human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation techniqueSMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decayLocalization of nucleoporin Tpr to the nuclear pore complex is essential for Tpr mediated regulation of the export of unspliced RNA.Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decaySMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoanAn unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decayInteractions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathwaysA new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translationUpf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decayA competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decayUnusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing.Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayStructures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complexRNA granulesNonsense-mediated mRNA decay: novel mechanistic insights and biological impactMechanism and regulation of the nonsense-mediated decay pathwayThe dharma of nonsense-mediated mRNA decay in mammalian cellsNonsense-mediated mRNA decay: inter-individual variability and human diseasePhospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5–SMG7 and SMG6Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiae.Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay.P bodies promote stress granule assembly in Saccharomyces cerevisiae.Targeting of aberrant mRNAs to cytoplasmic processing bodies.Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryTTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elementsLocalization of AU-rich element-containing mRNA in cytoplasmic granules containing exosome subunitsOrganizing principles of mammalian nonsense-mediated mRNA decayHow and where are nonsense mRNAs degraded in mammalian cells?Mitochondria associate with P-bodies and modulate microRNA-mediated RNA interference.High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection.Current knowledge of MicroRNAs and noncoding RNAs in virus-infected cells.Emergence of a complex relationship between HIV-1 and the microRNA pathway.The mRNP remodeling mediated by UPF1 promotes rapid degradation of replication-dependent histone mRNA.A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.When a ribosome encounters a premature termination codon.ARE-mRNA degradation requires the 5'-3' decay pathway.Role of the DHH1 gene in the regulation of monocarboxylic acids transporters expression in Saccharomyces cerevisiae.
P2860
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P2860
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@ast
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@en
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@nl
type
label
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@ast
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@en
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@nl
prefLabel
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@ast
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@en
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@nl
P1433
P1476
SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.
@en
P304
P356
10.1016/J.MOLCEL.2004.10.013
P577
2004-11-01T00:00:00Z