Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
about
The glmS ribozyme cofactor is a general acid-base catalystUse of a coenzyme by the glmS ribozyme-riboswitch suggests primordial expansion of RNA chemistry by small moleculesDynamic energy landscapes of riboswitches help interpret conformational rearrangements and function.Phosphatase-inert glucosamine 6-phosphate mimics serve as actuators of the glmS riboswitch.Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulationsThe glmS ribozyme tunes the catalytically critical pK(a) of its coenzyme glucosamine-6-phosphateMolecular mechanism for preQ1-II riboswitch function revealed by molecular dynamics.Structural insights into the interactions of xpt riboswitch with novel guanine analogues: a molecular dynamics simulation study.Divalent Metal Ion Activation of a Guanine General Base in the Hammerhead Ribozyme: Insights from Molecular Simulations.An active-site guanine participates in glmS ribozyme catalysis in its protonated stateChemical feasibility of the general acid/base mechanism of glmS ribozyme self-cleavage.Assessing the Potential Effects of Active Site Mg2+ Ions in the glmS Ribozyme-Cofactor ComplexAn expanded collection and refined consensus model of glmS ribozymes.Mechanism and distribution of glmS ribozymes.Rapid steps in the glmS ribozyme catalytic pathway: cation and ligand requirements.Magnesium-induced nucleophile activation in the guanylyltransferase mRNA capping enzyme.glmS Riboswitch binding to the glucosamine-6-phosphate α-anomer shifts the pKa toward neutrality.RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.
P2860
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P2860
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
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2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@ast
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@en
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@nl
type
label
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@ast
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@en
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@nl
prefLabel
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@ast
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@en
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@nl
P2860
P356
P1433
P1476
Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozyme
@en
P2093
Donald Hamelberg
P2860
P304
P356
10.1261/RNA.2334110
P407
P577
2010-10-22T00:00:00Z