Microtubulin binding sites as target for developing anticancer agents.
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Role of Bim in apoptosis induced in H460 lung tumor cells by the spindle poison Combretastatin-A4KPU-300, a Novel Benzophenone-Diketopiperazine-Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M PhaseMitotic slippage in non-cancer cells induced by a microtubule disruptor, disorazole C1.Antitumor peptides from marine organismsN-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a new scaffold that provides rapid access to antimicrotubule agents: synthesis and evaluation of antiproliferative activity against select cancer cell lines.Herbal medicine as inducers of apoptosis in cancer treatment.A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization.Chemistry and biology of monoterpene indole alkaloid biosynthesis.Tubulin inhibitor identification by bioactive conformation alignment pharmacophore-guided virtual screening.Antitumor agents. 256. Conjugation of paclitaxel with other antitumor agents: evaluation of novel conjugates as cytotoxic agentsSynthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.Microtubule inhibitors as a potential treatment for malaria.Prodrug strategies in anticancer chemotherapy.Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity.A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression.From amino acid sequence to bioactivity: The biomedical potential of antitumor peptides.Antiproliferative activity of yatein isolated from Austrocedrus chilensis against murine myeloma cells: cytological studies and chemical investigations.Linobiflavonoid inhibits human lung adenocarcinoma A549 cells: effect on tubulin protein.Natural Compounds as Modulators of Cell Cycle Arrest: Application for Anticancer Chemotherapies.Synthesis and antitumor evaluation of nitrovinyl biphenyls: anticancer agents based on allocolchicines.Lupeol triterpene, a novel diet-based microtubule targeting agent: disrupts survivin/cFLIP activation in prostate cancer cells.The tubulin-depolymerising agent combretastatin-4 induces ectopic aster assembly and mitotic catastrophe in lung cancer cells H460.Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of beta-tubulin.Modeling Cancer Cell Growth Dynamics In vitro in Response to Antimitotic Drug TreatmentN-4-iodophenyl-N'-2-chloroethylurea, a novel potential anticancer agent with colon-specific accumulation: radioiodination and comparative in vivo biodistribution profiles.Enhanced therapeutic effects on the multi-drug resistant human leukemia cells in vitro and xenograft in mice using the stealthy liposomal vincristine plus quinacrine.In vitro effects of an in silico-modelled 17β-estradiol derivative in combination with dichloroacetic acid on MCF-7 and MCF-12A cells.Stilbene derivatives that are colchicine-site microtubule inhibitors have antileukemic activity and minimal systemic toxicity.Synthesis, in vitro and in vivo evaluation of new hybrids of millepachine and phenstatin as potent tubulin polymerization inhibitors.The GPER agonist G-1 induces mitotic arrest and apoptosis in human vascular smooth muscle cells independent of GPER.
P2860
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P2860
Microtubulin binding sites as target for developing anticancer agents.
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Microtubulin binding sites as target for developing anticancer agents.
@ast
Microtubulin binding sites as target for developing anticancer agents.
@en
Microtubulin binding sites as target for developing anticancer agents.
@nl
type
label
Microtubulin binding sites as target for developing anticancer agents.
@ast
Microtubulin binding sites as target for developing anticancer agents.
@en
Microtubulin binding sites as target for developing anticancer agents.
@nl
prefLabel
Microtubulin binding sites as target for developing anticancer agents.
@ast
Microtubulin binding sites as target for developing anticancer agents.
@en
Microtubulin binding sites as target for developing anticancer agents.
@nl
P356
P1476
Microtubulin binding sites as target for developing anticancer agents
@en
P2093
Magdy N Iskander
P304
P356
10.2174/1389557043402946
P50
P577
2004-12-01T00:00:00Z