Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity.

Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity.

Item
http://www.wikidata.org/entity/Q37342450
A Novel Nitrobenzoate Microtubule Inhibitor that Overcomes Multidrug Resistance Exhibits Antitumor ActivityIC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.An overview of tubulin inhibitors that interact with the colchicine binding sitePreparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and PyrrolesNew microtubule-inhibiting anticancer agents.Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules.Green synthesis of bacterial mediated anti-proliferative gold nanoparticles: inducing mitotic arrest (G2/M phase) and apoptosis (intrinsic pathway).Design and synthesis of pyrazole/isoxazole linked arylcinnamides as tubulin polymerization inhibitors and potential antiproliferative agents.Interaction of Aβ peptide with tubulin causes an inhibition of tubulin polymerization and the apoptotic death of cancer cells.Effects of the tumor-vasculature-disrupting agent verubulin and two heteroaryl analogues on cancer cells, endothelial cells, and blood vessels.Synthesis and bioevaluation of diphyllin glycosides as novel anticancer agents.Albendazole as a promising molecule for tumor control.Target Based Designing of Anthracenone Derivatives as Tubulin Polymerization Inhibiting Agents: 3D QSAR and Docking Approach.Overexpressed HDAC8 in cervical cancer cells shows functional redundancy of tubulin deacetylation with HDAC6.Copper-Catalyzed Syntheses of Pyrene-Pyrazole Pharmacophores and Structure Activity Studies for Tubulin Polymerization
P2860

Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity.

Item
http://www.wikidata.org/entity/Q37342450
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Novel microtubule polymerizati ...... rative and antitumor activity.
@en
Novel microtubule polymerizati ...... rative and antitumor activity.
@nl
type
label
Novel microtubule polymerizati ...... rative and antitumor activity.
@en
Novel microtubule polymerizati ...... rative and antitumor activity.
@nl
prefLabel
Novel microtubule polymerizati ...... rative and antitumor activity.
@en
Novel microtubule polymerizati ...... rative and antitumor activity.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
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P1476
Novel microtubule polymerizati ...... rative and antitumor activity.
@en
P2093
P2860
P304
P31
P356
10.1158/0008-5472.CAN-08-0877
P407
P433
P478
P577
P698
P932