Expansion of CUG RNA repeats causes stress and inhibition of translation in myotonic dystrophy 1 (DM1) cells
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Feedback Regulation of Kinase Signaling Pathways by AREs and GREsCongenital and childhood myotonic dystrophy: Current aspects of disease and future directionsMuscle wasting in myotonic dystrophies: a model of premature agingRAN translation and frameshifting as translational challenges at simple repeats of human neurodegenerative disordersDisease Phenotypes in a Mouse Model of RNA Toxicity Are Independent of Protein Kinase Cα and Protein Kinase CβHypogonadism Associated with Cyp19a1 (Aromatase) Posttranscriptional Upregulation in Celf1 Knockout Mice.RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1Native tertiary structure and nucleoside modifications suppress tRNA's intrinsic ability to activate the innate immune sensor PKR.Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy.High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.Massive expansion of SCA2 with autonomic dysfunction, retinitis pigmentosa, and infantile spasmsThe role of the immune system in triplet repeat expansion diseasesRNA Foci, CUGBP1, and ZNF9 are the primary targets of the mutant CUG and CCUG repeats expanded in myotonic dystrophies type 1 and type 2CUG-BP1 regulates RyR1 ASI alternative splicing in skeletal muscle atrophy.Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation.GSK3β mediates muscle pathology in myotonic dystrophyCompetitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function.CELFish ways to modulate mRNA decay.Staufen1 impairs stress granule formation in skeletal muscle cells from myotonic dystrophy type 1 patients.STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdownMolecular mechanisms of muscle atrophy in myotonic dystrophies.Myotonic dystrophy mouse models: towards rational therapy development.GSK3β is a new therapeutic target for myotonic dystrophy type 1.The role of CUGBP1 in age-dependent changes of liver functions.Skeletal muscle features in myotonic dystrophy and sarcopenia: do similar nuclear mechanisms lead to skeletal muscle wasting?RNA Transcription and Maturation in Skeletal Muscle Cells are Similarly Impaired in Myotonic Dystrophy and Sarcopenia: The Ultrastructural Evidence.Molecular mechanisms in DM1 - a focus on foci.Activation of the innate immune response and interferon signalling in myotonic dystrophy type 1 and type 2 cataracts.(CCUG)n RNA toxicity in a Drosophila model of myotonic dystrophy type 2 (DM2) activates apoptosis.p300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways.Muscleblind-like1 undergoes ectopic relocation in the nuclei of skeletal muscles in myotonic dystrophy and sarcopenia.Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1.Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome.Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin-NFAT signaling in skeletal muscle of DM1 mice.Cells of Matter-In Vitro Models for Myotonic Dystrophy.Bruno-3 regulates sarcomere component expression and contributes to muscle phenotypes of myotonic dystrophy type 1.miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models.RNA processing is altered in skeletal muscle nuclei of patients affected by myotonic dystrophy
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P2860
Expansion of CUG RNA repeats causes stress and inhibition of translation in myotonic dystrophy 1 (DM1) cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Expansion of CUG RNA repeats c ...... otonic dystrophy 1 (DM1) cells
@ast
Expansion of CUG RNA repeats c ...... otonic dystrophy 1 (DM1) cells
@en
Expansion of CUG RNA repeats c ...... lation in myotonic dystrophy 1
@nl
type
label
Expansion of CUG RNA repeats c ...... otonic dystrophy 1 (DM1) cells
@ast
Expansion of CUG RNA repeats c ...... otonic dystrophy 1 (DM1) cells
@en
Expansion of CUG RNA repeats c ...... lation in myotonic dystrophy 1
@nl
prefLabel
Expansion of CUG RNA repeats c ...... otonic dystrophy 1 (DM1) cells
@ast
Expansion of CUG RNA repeats c ...... otonic dystrophy 1 (DM1) cells
@en
Expansion of CUG RNA repeats c ...... lation in myotonic dystrophy 1
@nl
P2093
P2860
P356
P1433
P1476
Expansion of CUG RNA repeats c ...... otonic dystrophy 1 (DM1) cells
@en
P2093
Bingwen Jin
Claudia Huichalaf
Guo-Li Wang
Karlie Jones
Keiko Sakai
Lubov Timchenko
Nikolai Timchenko
Olivia M Pereira-Smith
Partha Sarkar
P2860
P304
P356
10.1096/FJ.09-151159
P407
P577
2010-05-17T00:00:00Z